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3028437

amolin19 edited this page May 18, 2021 · 1 revision

3028437 - Cholesterol in LDL [Mass/volume] in Serum or Plasma

Cholesterol is a waxy substance found in your blood. Your body needs cholesterol to build healthy cells, but high levels of cholesterol can increase your risk of heart disease. Cholesterol is carried through your blood, attached to proteins. This combination of proteins and cholesterol is called a lipoprotein. There are different types of cholesterol, based on what the lipoprotein carries. They are:

  • Low-density lipoprotein (LDL). LDL, or "bad" cholesterol, transports cholesterol particles throughout your body. LDL cholesterol builds up in the walls of your arteries, making them hard and narrow.
  • High-density lipoprotein (HDL). HDL, or "good" cholesterol, picks up excess cholesterol and takes it back to your liver. 1

8840

In the OMOP vocabulary 8840 is a Standard Concept that represents the unit milligram per deciliter (mg/dL)

Plausible Low Value

20

Plausible High Value

300.00

Rationale

LDL is considered low if it is less than 40 mg/dL, while there are people with rare inherited disorders in which LDL levels are often less than 30 mg/dL 3. With statins, LDL has been observed to be as low as 20 mg/dL. LDL is considered very high if greater than 190 mg/dL 4. This information combined with a data-driven approach to empirically establish possible low and high values, leads us to choose 20 and 300.

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