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Estradiol, also called E2, is the main female hormone made by nonpregnant women. 1 This test measures the amount of estradiol (E2), the form of estrogen made mainly by the ovaries. E2 plays a key role in the development of the female reproduction system, including the uterus, fallopian tubes, vagina, and breasts. Women have higher amounts of E2 during their reproductive years and almost none after menopause. In men, E2 is secreted in moderate amounts by the testes throughout life. 2
Estradiol tests are useful for: 1
- Determining the reason for early or late puberty in girls
- Determining the reason for late puberty in boys
- Diagnosing menstrual problems
- Determining the cause of infertility
- Monitoring infertility treatments
- Monitoring treatments for menopause
- Finding tumors that make estrogen
In the OMOP vocabulary 8845 is a Standard Concept that represents the unit picogram per milliliter (pg/mL)
0
40000.0
During pregnancy, E2 can be as high as 30,000 pg/mL 3 to 40,000 pg/mL 4. It is possible that children ranging in age from 14 days to prepubescence, will have undetectable levels of E2 5 and zero should be the plausible low value.