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3024128
Bilirubin is a yellowish pigment that is made during the normal breakdown of red blood cells. Bilirubin passes through the liver and is eventually excreted out of the body. A bilirubin test measures the levels of bilirubin in your blood. Higher than normal levels of bilirubin may indicate different types of liver or bile duct problems. Bilirubin testing is usually done as part of a group of tests to check the health of your liver. Bilirubin testing may be done to:
- Investigate jaundice — a yellowing of the skin and eyes caused by elevated levels of bilirubin. A common use of this test is to measure bilirubin levels in newborns to check for infant jaundice.
- Determine whether there might be blockage in your bile ducts, in either the liver or the gallbladder.
- Help detect liver disease, particularly hepatitis, or monitor its progression.
- Help evaluate anemia caused by the destruction of red blood cells.
- Help follow how a treatment is working.
- Help evaluate a suspected drug toxicity. 1
In the OMOP vocabulary 3024128 is a Standard Concept that represents the measurement Bilirubin.total [Mass/volume] in Serum or Plasma
The recommended low and high values for each unit associated with 3023884 are below. These are not meant to be normal values. Rather, these are meant to be biologically plausible values. For example, it would be implausible to see a patient with a weight of 0 kg though a person could be 2.5 kg.
In the OMOP vocabulary 8840 is a Standard Concept that represents the unit milligram/deciliter (mg/dL)
0
100.0
The range 0-100 was chosen based on values seen in real world data. Low total bilirubin level in the blood is called hypobilirubinemia.
According to 2, hypobilirubinemia is not common and it is not an issue of concern. There are some labs that consider zero or not detected bilirubin level in the blood as normal value.
However, recent studies consider that there is a relationship between low serum bilirubin level and an increased risk of cardiovascular
disease (angina pectoris, heart attack, etc.). Normal bilirubin levels are generally less than 1 milligram per deciliter (mg/dL) 3,
with a common range of .3 mg/dL to 1.2 mg/dL found in the literature. 4
Hyperbilirubinemia, high total bilirubin level in the blood, is one of the most common problems encountered in term newborns,
with values ranging from 12 mg/dL to 20 mg/dL 6. Extreme hyperbilirubinemia occurs when total bilirubin is at least 25 mg/dL
and instances of infants with at least 50 mg/dL can be observed in the literature as well. 7