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Update description #267

Merged
merged 2 commits into from
Aug 13, 2024
Merged

Update description #267

merged 2 commits into from
Aug 13, 2024

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joverlee521
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Description of proposed changes

Updating the shared description.md for all builds:

  • future proof GitHub URLs by switching master to -
  • update URL for the clades.tsv to reflect move to phylogenetic/
  • add link to clade I build

Related issue(s)

Resolves #266

Checklist

  • Checks pass

- future proof by switching `master` to `-`
- update URL for the clades.tsv to reflect move to `phylogenetic/`

The first is [`mpox/lineage-B.1`](https://nextstrain.org/mpox/lineage-B.1), which focuses on lineage B.1 of the global outbreak that started in 2022 and includes as many sequences as possible. Here, we conduct a molecular clock analysis in which evolutionary rate is estimated from the data (with a resulting estimate of ~6 &times; 10<sup>-5</sup> subs per site per year).

The second is [`mpox/clade-IIb`](https://nextstrain.org/mpox/clade-IIb), which focuses on recent viruses transmitting from human-to-human and includes viruses belonging to clade IIb. All good quality sequences that are not lineage B.1 are included, while lineage B.1 sequences is heavily subsampled to allow non-B.1 diversity to be studied.Here, we also conduct a molecular clock analysis in which evolutionary rate is estimated from the data (with a resulting estimate of ~6 &times; 10<sup>-5</sup> subs per site per year).

The third is [`mpox/all-clades`](https://nextstrain.org/mpox/all-clades), which focuses on broader viral diversity and includes viruses from the animal reservoir and previous human outbreaks, encompassing clades I, IIa and IIb as described in [Happi et al](https://doi.org/10.1371/journal.pbio.3001769) and endorsed by a [WHO convened consultation](https://worldhealthorganization.cmail20.com/t/ViewEmail/d/422BD62D623B6A3D2540EF23F30FEDED/F75AF81C90108C72B4B1B1F623478121?alternativeLink=False).

The fourth is [`mpox/clade-I`](https://nextstrain.org/mpox/clade-I), which focuses on clade I sequences and includes as many sequences as possible.
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@jameshadfield Feel free to update this if there is more you would like to add about the clade I build.

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Looks good, thanks!

@joverlee521 joverlee521 merged commit 0771196 into master Aug 13, 2024
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@joverlee521 joverlee521 deleted the update-description branch August 13, 2024 17:06
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Add clade I to the phylogenetic description.md
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