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Process GPML changes
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actions-user committed Aug 8, 2024
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223 changes: 112 additions & 111 deletions pathways/WP124/WP124.gpml

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664 changes: 367 additions & 297 deletions pathways/WP2525/WP2525.gpml

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1,608 changes: 800 additions & 808 deletions pathways/WP5055/WP5055.gpml

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2,158 changes: 1,114 additions & 1,044 deletions pathways/WP5083/WP5083.gpml

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3,408 changes: 1,701 additions & 1,707 deletions pathways/WP5094/WP5094.gpml

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1,425 changes: 713 additions & 712 deletions pathways/WP5098/WP5098.gpml

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60 changes: 47 additions & 13 deletions pathways/WP533/WP533.gpml
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<?xml version="1.0" encoding="UTF-8"?>
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Lysine biosynthesis" Data-Source="WikiPathways" Version="WP533_r130617" Author="[M.Braymer, MaintBot, Ddigles, Egonw, Eweitz, Khanspers]" Last-Modified="20240529044202" Organism="Saccharomyces cerevisiae">
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Lysine biosynthesis" Data-Source="WikiPathways" Version="WP533_r135187" Author="[M.Braymer, MaintBot, Ddigles, Egonw, Eweitz, Khanspers]" Last-Modified="20240807133705" Organism="Saccharomyces cerevisiae">
<Comment Source="WikiPathways-description">S. cerevisiae synthesizes the essential amino acid L-lysine via the L-alpha-aminoadipic acid pathway instead of the diaminopmelate pathway (CITS: [10714900]). Originally proposed to be characteristic of fungi, recent studies suggest prokaryotes also synthesize lysine via the alpha-aminoadipic acid pathway (CITS: [11029074]). Intermediates in this pathway are often incorporated into secondary metabolites. For example, it has been well- studied that alpha-aminoadipate is required for penicillin production (CITS: [10714900]). Regulation of the lysine biosynthetic pathway in S. cerevisiae is an interaction between general amino acid control (via Gcn4p) (CITS: [Hinnebusch]), feedback inhibition of homocitrate synthase activity by lysine (CITS: [10103047]), and induction of Lys14p by alpha-aminoadipate semialdehyde (CITS: [10975256]).
SOURCE: SGD pathways, http://pathway.yeastgenome.org/server.html</Comment>
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<BiopaxRef>f64</BiopaxRef>
<BiopaxRef>d19</BiopaxRef>
<Graphics BoardWidth="1084.9999999999911" BoardHeight="780.5168067226882" />
<DataNode TextLabel="LYS12" GraphId="a04" Type="GeneProduct">
<Attribute Key="org.pathvisio.model.BackpageHead" Value="LYS12" />
Expand Down Expand Up @@ -467,18 +470,6 @@ SOURCE: SGD pathways, http://pathway.yeastgenome.org/server.html</Comment>
<Group GroupId="aaac2" GraphId="ea325" Style="Group" />
<InfoBox CenterX="5.0" CenterY="578.3333333333334" />
<Biopax>
<bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
<bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">lysine biosynthetic pathway</bp:TERM>
<bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000074</bp:ID>
<bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
</bp:openControlledVocabulary>
<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="cfd">
<bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:ID>
<bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
<bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">L-lysine biosynthesis IV</bp:TITLE>
<bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://biocyc.org/pathway?orgid=META&amp;id=LYSINE-AMINOAD-PWY</bp:SOURCE>
<bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:YEAR>
</bp:PublicationXref>
<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="nvb">
<bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">10714900</bp:ID>
<bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
Expand All @@ -488,11 +479,54 @@ SOURCE: SGD pathways, http://pathway.yeastgenome.org/server.html</Comment>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Zabriskie TM</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Jackson MD</bp:AUTHORS>
</bp:PublicationXref>
<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="f64">
<bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">10103047</bp:ID>
<bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
<bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p.</bp:TITLE>
<bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Eur J Biochem</bp:SOURCE>
<bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1999</bp:YEAR>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Feller A</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Ramos F</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Piérard A</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dubois E</bp:AUTHORS>
</bp:PublicationXref>
<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="d19">
<bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">10975256</bp:ID>
<bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
<bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Characterisation of a tripartite nuclear localisation sequence in the regulatory protein Lys14 of Saccharomyces cerevisiae.</bp:TITLE>
<bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Curr Genet</bp:SOURCE>
<bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2000</bp:YEAR>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">El Alami M</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Feller A</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Piérard A</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Dubois E</bp:AUTHORS>
</bp:PublicationXref>
<bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
<bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">lysine biosynthetic pathway</bp:TERM>
<bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000074</bp:ID>
<bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
</bp:openControlledVocabulary>
<bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
<bp:TERM xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">classic metabolic pathway</bp:TERM>
<bp:ID xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PW:0000002</bp:ID>
<bp:Ontology xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pathway Ontology</bp:Ontology>
</bp:openControlledVocabulary>
<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="f0b">
<bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11029074</bp:ID>
<bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
<bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">What is characteristic of fungal lysine synthesis through the alpha-aminoadipate pathway?</bp:TITLE>
<bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">J Mol Evol</bp:SOURCE>
<bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2000</bp:YEAR>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nishida H</bp:AUTHORS>
<bp:AUTHORS rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Nishiyama M</bp:AUTHORS>
</bp:PublicationXref>
<bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="cfd">
<bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://biocyc.org/pathway?orgid=META&amp;id=LYSINE-AMINOAD-PWY</bp:ID>
<bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">URL</bp:DB>
<bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">L-lysine biosynthesis IV</bp:TITLE>
<bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://biocyc.org/pathway?orgid=META&amp;id=LYSINE-AMINOAD-PWY</bp:SOURCE>
<bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:YEAR>
</bp:PublicationXref>
</Biopax>
</Pathway>

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