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Should normalized counts be scaled before running PCA?
I was just looking through the dimensionality reduction section and noticed that you use the log1p_norm counts for the PCA. Is there a particular reason for not applying scaling before PCA as a best practice approach?
Thank you for your time and resources!
The text was updated successfully, but these errors were encountered:
Should normalized counts be scaled before running PCA?
I was just looking through the dimensionality reduction section and noticed that you use the log1p_norm counts for the PCA. Is there a particular reason for not applying scaling before PCA as a best practice approach?
Thank you for your time and resources!
The text was updated successfully, but these errors were encountered: