Go to the blocksuniverse directory, and run
pip install -r requirements.txt
python manage.py migrate
and then to blocksuniverse/frontend, and run
npm install
to install the required dependencies.
First, run the server from blocksuniverse:
python manage.py runserver
Then, run gulp from blocksuniverse/frontend:
./gulp
You're good to go! Test that everything works on localhost:8000.