NCI Thesaurus 2023.11d

sigven · Dec 12, 2023 · 64bdb55 · 64bdb55
1 parent 99aaec2
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diff --git a/DESCRIPTION b/DESCRIPTION
@@ -2,7 +2,7 @@ Package: pharmOncoX
 Type: Package
 Title: Molecularly targeted cancer drugs and biomarkers
 Version: 1.4.8
-Date: 2023-11-30
+Date: 2023-12-12
 Authors@R: 
  c(person(given = "Sigve",
  family = "Nakken",

diff --git a/NEWS.md b/NEWS.md
@@ -1,3 +1,8 @@
+# Version 1.4.8 (December 12th 2023)
+
+* Updated NCI Thesaurus - 23.11d
+* Updated CIViC data (20231212)
+
 # Version 1.4.8 (November 30th 2023)
 
 * Updated OTP (v2023.12)

diff --git a/R/sysdata.rda b/R/sysdata.rda
diff --git a/data-raw/custom_drug_target_regex_nci.tsv b/data-raw/custom_drug_target_regex_nci.tsv
@@ -10,8 +10,18 @@ Garsorasib KRAS
 Anti-BTLA BTLA
 Cifurtilimab CD40
 MRTX1133 KRAS
+Fexagratinib FGFR1
+Fexagratinib FGFR2
+Fexagratinib FGFR3
+Fexagratinib FGFR4
+Firmonertinib EGFR
+HIF-2alpha Inhibitor EPAS1
+HMGB1 Inhibitor HMGB1
 Izalontamab HER1
 Izalontamab ERBB3
+DGK-alpha Inhibitor DGKH
+DGKalpha Inhibitor DGKH
+DNA Polymerase Theta Inhibitor POLQ
 ALDH1/3 Inhibitor ABD-3001 ALDH1
 ALDH1/3 Inhibitor ABD-3001 ALDH3
 Anti-Claudin-18.2|Anti-CLDN18.2 Monoclonal CLDN18

diff --git a/data-raw/data-raw.R b/data-raw/data-raw.R
@@ -74,7 +74,7 @@ drug_sets <- list()
 ## Get all anticancer drugs, NCI thesaurus + DGIdb
 drug_sets[['nci']] <- get_nci_drugs(
  nci_db_release = nci_db_release,
- overwrite = F,
+ overwrite = T,
  path_data_raw = path_data_raw,
  path_data_processed = path_data_tmp_processed)
 

diff --git a/data-raw/metadata_pharm_oncox.xlsx b/data-raw/metadata_pharm_oncox.xlsx