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diffRepsOutput

Li Shen edited this page Mar 19, 2015 · 1 revision

Explanation of the diffReps' columns

Column Name Explanation
Chrom Chromosome name
Start 1-based start coordinate
End 1-based end coordinate (inclusive)
Length Length of the differential site in bps
Treatment.cnt Normalized read counts of the treatment group (separated by semi-colon)
Control.cnt Normalized read counts of the control group (separated by semi-colon)
Treatment.avg Avg. count (normalized) of the treatment group
Control.avg Avg. count (normalized) of the control group
Treatment.enr Fold enrichment vs. input based on avg. count (normalized) for treatment group
Control.enr Fold enrichment vs. input based on avg. count (normalized) for control group
Event Direction of enrichment change using the control group as reference
log2FC Log2 fold change
pval P-value
padj BH-adjusted p-value (FDR)
winSta Start coordinate of the core window which is the window with most significant p-value among the site
winEnd End coordinate of the core window
winFC Log2 fold change of the core window
winP P-value of the core window
winQ Adjusted p-value of the core window
GName Associated gene name
TName Associated transcript name
Strand Associated transcription strand
TSS Associated transcript start site
TES Associated transcript end site
Feature Classification of the site's location
D2TSS Distance from the site center to the associated transcript's TSS

findHotspots

Column Name Explanation
Chrom Chromosome name
Start 1-based start coordinate
End 1-based end coordinate (inclusive)
Length Length of the hotspot in bps
enrich Enrichment ratio (compared with background)
pval P-value of enrichment
padj Adjusted p-value
nsite Number of differential sites in the hotspot
Sites One-string description of the hotspots. The differential sites are separated by semi-colon. Each differential site is described by filename:(info columns separated by comma):line_number.
ntype Number of different types of chromatin marks in the hotspot
MarkType Unique chromatin marks in the hotspot. In order for findHotspots to recognize mark names, you must make the diffReps output file names contain "standard" chromatin mark names. Such as, diffout.h3k4me3.txt, diffout.h3k9ac.txt, diffout.polII.txt. If it cannot recognize the marks, it will put the whole file names here.
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