Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Replace supplies and drains relations by more specific relations #3426

Open
wants to merge 3 commits into
base: master
Choose a base branch
from

Conversation

gouttegd
Copy link
Collaborator

RO now provides 'vessel supplies blood to' (RO:0020101) as a more specific variant of 'supplies' (RO:0002178). The new relation is domain-restricted to 'blood vessel' (UBERON:0001981). In this PR, we use the new relation wherever 'supplies' was used to qualify a blood vessel.

Likewise for 'vessel drains blood from' (RO:0020102), which is a more specific variant of 'drains' (RO:0002179).

Recently introduced patterns for arteries and veins (in #3288) already use the more specific relations, so this improves Uberon’s consistency. More importantly, no longer using 'supplies' and 'drains' wherever a blood vessel is involved means that we no longer need to inject our own domain restrictions to those relations, so we can remove those injections as well (#2453).

The new relations are range-restricted in RO to (material) 'anatomical structure', which causes two side-effects:

RO now provides 'vessel supplies blood to' (RO:0020101) as a more
specific variant of 'supplies' (RO:0002178). The new relation is
domain-restricted to 'blood vessel' (UBERON:0001981). We use that new
relation wherever 'supplies' was used to qualify a blood vessel.

Likewise for 'vessel drains blood from' (RO:0020102), which is a more
specific variant of 'drains' (RO:0002179).

Recently introduced patterns for arteries and veins (#3288) already use
the more specific relations.

No longer using 'drains' and 'supplies' wherever a blood vessel is
involved means that we no longer need to inject our own domain and range
restrictions to those relations, so we remove those injections as well
(#2453).
'supraorbital artery' (UBERON:0015160) supplies blood to the 'frontal
sinus' (UBERON:0001760), but 'frontal sinus' represents an immaterial
anatomical cavity, and is therefore incompatible with the range
restriction of the 'vessel supplies blood to' (RO:0020101) relation.

We replace the object of that relation to 'mucosa of frontal sinus' (a
material anatomical entity) instead.
The 'intercostal vein' (UBERON:0012197) and 'intercostal artery'
(UBERON:0005612) are said to drain and supply blood from and to the
'intercostal space' (UBERON:0012198).

In both cases, this violates the range restriction of the 'vessel drains
blood from' (RO:0020102) and 'vessel supplies blood to' (RO:0020101)
relations, because 'intercostal space' is an immaterial anatomical
entity.

We create a new term 'intercostal element' intended to refer to any
anatomical structure located within an intercostal space (e.g.
intercostal muscles, intercostal lymph nodes), and use the new term to
replace 'intercostal space' in the relationships with 'intercostal vein'
and 'intercostal arteries'.
@gouttegd gouttegd self-assigned this Nov 14, 2024
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

Successfully merging this pull request may close these issues.

1 participant