Merge pull request #3422 from obophenotype/3421-stratum-spinosum-of-e…

…sophageal-epithelium

stratum spinosum of esophageal epithelium

src/ontology/uberon-edit.obo

@@ -224694,6 +224694,15 @@ is_a: UBERON:0004693 ! Peyer's patch epithelium
 relationship: dc-contributor https://orcid.org/0009-0005-7919-4905
 property_value: dcterms-date "2024-11-07T11:44:27Z" xsd:dateTime
 
+[Term]
+id: UBERON:8700002
+name: stratum spinosum of esophageal epithelium
+def: "The second deepest layer of the stratified squamous epithelium lining the esophagus, positioned directly above the stratum basale. It consists of multiple layers of keratinocytes connected by strong intercellular junctions called desmosomes, giving the cells a characteristic \"spiny\" appearance. This layer provides structural support, contributes to the epithelial barrier function, and serves as a transitional zone for keratinocytes migrating towards the luminal surface, playing a crucial role in maintaining the integrity and protective properties of the esophageal lining." [PMID:21126700, PMID:26019440]
+is_a: UBERON:0010304 ! non-keratinized stratified squamous epithelium
+relationship: dc-contributor https://orcid.org/0009-0005-7919-4905
+relationship: part_of UBERON:0001043 ! esophagus
+property_value: dcterms-date "2024-11-14T15:00:21Z" xsd:dateTime
+
 [Term]
 id: UBERON:8850000
 name: lumen of pulmonary alveolus