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Update EGFR network with edge directions
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agitter committed Sep 22, 2023
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Expand Up @@ -46,7 +46,7 @@ The following files are very small toy datasets used to illustrate the supported
This dataset represents protein phosphorylation changes in response to epidermal growth factor (EGF) treatment.
The network includes protein-protein interactions from [iRefIndex](http://irefindex.org/) and kinase-substrate interactions from [PhosphoSitePlus](http://www.phosphosite.org/).
The files are originally from the [Temporal Pathway Synthesizer (TPS)](https://github.com/koksal/tps) repository.
They have been lightly modified for SPRAS by lowering one edge weight that was greater than 1, removing a PSEUDONODE prize, adding a prize of 10.0 to EGF_HUMAN, and converting all edges to undirected edges.
They have been lightly modified for SPRAS by lowering one edge weight that was greater than 1, removing a PSEUDONODE prize, and adding a prize of 10.0 to EGF_HUMAN.
The only source is EGF_HUMAN.
All proteins with phosphorylation-based prizes are also labeled as targets.
All nodes are considered active.
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