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Welcome to BST 270: Reproducible Data Science

Instructor: Heather Mattie ([email protected])

TA: Matthew West ([email protected])

January 11-15, 19-21, 9am-12pm

Heather's office hour: by appointment

Matthew's office hour: TBD

Purpose of the course

Reproducible research has become increasingly important in the biomedical sciences. The science community has recognized reproducibility is a growing challenge in basic, clinical and population sciences. Experimental design, data provenance, analytic methods and tools, and reporting science play a critical role in the biomedical research ecosystem to ensure scientific rigor, robustness and transparency. Statistical and computational methods and tools are fundamental for making scientific results reproducible.

Course structure

The central theme of the course will be to meet these scientific needs of reproducible science through training in reproducible research. The topics covered in this course include the fundamentals of reproducible science, case studies in reproducible research, data provenance, statistical methods for reproducible science, and computational tools for reproducible science. This is a blended course where students are introduced to course content online through videos and reading assignments, and then shown how to use the tools and methods described in the videos to conduct reproducible research. The online videos can be found on edx.org - the course title is Principles, Statistical and Computational Tools for Reproducible Science. In class we will attempt to reproduce the results of a recently published paper and then critique its reproducibility. Students will also complete an individual project.

Recommended reading

  1. Christopher Gandrud (2015), Reproducible Research with R and RStudio, 2nd Ed.
  2. The Practice of Reproducible Research: Case Studies and Lessons from the Data-Intensive Sciences, 1st Ed.

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