dynamice

DynaMICE (Dynamic Measles Immunisation Calculation Engine) is an age-structured compartmental model for measles transmission and vaccination.

Details of model structure and assumptions can be found in the following references:

• Fu H, Abbas K, Klepac P, van Zandvoort K, Tanvir H, Portnoy A, et al. Effect of evidence updates on key determinants of measles vaccination impact: a DynaMICE modelling study in ten high-burden countries. BMC Med. 2021;19(1):281.
  • https://doi.org/10.1186/s12916-021-02157-4
• Verguet S, Johri M, Morris SK, Gauvreau CL, Jha P, Jit M. Controlling measles using supplemental immunization activities: a mathematical model to inform optimal policy. Vaccine. 2015;33(10):1291-6.
  • https://doi.org/10.1016/j.vaccine.2014.11.050

The model has also been applied in the following studies to understand measles vaccination impact in different settings:

• Li X, Mukandavire C, Cucunuba ZM, Echeverria Londono S, Abbas K, Clapham HE, et al. Estimating the health impact of vaccination against ten pathogens in 98 low-income and middle-income countries from 2000 to 2030: a modelling study. Lancet. 2021;397(10272):398-408.
  • https://doi.org/10.1016/S0140-6736(20)32657-X
• Gaythorpe KA, Abbas K, Huber J, Karachaliou A, Thakkar N, Woodruff K, et al. Impact of COVID-19-related disruptions to measles, meningococcal A, and yellow fever vaccination in 10 countries. Elife. 2021;10.
  • https://doi.org/10.7554/eLife.67023
• Toor J, Echeverria-Londono S, Li X, Abbas K, Carter ED, Clapham HE, et al. Lives saved with vaccination for 10 pathogens across 112 countries in a pre-COVID-19 world. Elife. 2021;10.
  • https://doi.org/10.7554/eLife.67635