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imxj authored Apr 23, 2024
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- B.S. in Electronic Engineering and Information Science, University of Science and Technology of China, 2002

## Selected Research Projects
- *Applying Deep Learning to Drug Discovery*: [Our publication in the Journal of Medicinal Chemistry](https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.3c01471), for the first time, discovered a novel small molecule ligand for WDR91 by using affinity-mediated DNA-encoded chemical library selection followed by deep learning. WDRs’unique β-propeller structure makes them attractive targets, but most human WDRs are unexplored compared to other major drug target families. The discovery of a drug-like small molecule and its covalent analog compounds will soon enable researchers to identify a WDR91 drug candidate.
- *Studying secure communication from information theoretic perspective*: [Our publication in IEEE Transactions on Information Theory](https://ieeexplore.ieee.org/abstract/document/5238755) provided new insights into secure communication over broadcast channels by developing both inner and outer bounds for the rate equivocation region.
- Applying Deep Learning to Drug Discovery
- [Our publication in the Journal of Medicinal Chemistry](https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.3c01471), for the first time, discovered a novel small molecule ligand for WDR91 by using affinity-mediated DNA-encoded chemical library selection followed by deep learning. WDRs’unique β-propeller structure makes them attractive targets, but most human WDRs are unexplored compared to other major drug target families. The discovery of a drug-like small molecule and its covalent analog compounds will soon enable researchers to identify a WDR91 drug candidate.
- Studying secure communication from information theoretic perspective
- [Our publication in IEEE Transactions on Information Theory](https://ieeexplore.ieee.org/abstract/document/5238755) provided new insights into secure communication over broadcast channels by developing both inner and outer bounds for the rate equivocation region.


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