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from helical.models.hyena_dna.model import HyenaDNA,HyenaDNAConfig | ||
config = HyenaDNAConfig(model_name="hyenadna-tiny-1k-seqlen-d256") | ||
model = HyenaDNA(model_config=config) | ||
print("Done") |
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from .models.uce.model import UCEConfig, UCE | ||
from .models.geneformer.model import Geneformer,GeneformerConfig | ||
from .models.scgpt.model import scGPT, scGPTConfig | ||
from .models.hyena_dna.model import HyenaDNA, HyenaDNAConfig | ||
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from typing import Literal | ||
class HyenaDNAConfig(): | ||
def __init__( | ||
self, | ||
model_name: Literal["hyenadna-tiny-1k-seqlen", "hyenadna-tiny-1k-seqlen-d256"] = "hyenadna-tiny-1k-seqlen", | ||
n_layer: int = 2, | ||
vocab_size: int = 12, | ||
resid_dropout: float = 0.0, | ||
embed_dropout: float = 0.1, | ||
fused_mlp: bool = False, | ||
fused_dropout_add_ln: bool = True, | ||
residual_in_fp32: bool = True, | ||
pad_vocab_size_multiple: int = 8, | ||
return_hidden_state: bool = True, | ||
layer: dict = { | ||
"_name_": "hyena", | ||
"emb_dim": 5, | ||
"filter_order": 64, | ||
"local_order": 3, | ||
"l_max": 1026, | ||
"modulate": True, | ||
"w": 10, | ||
"lr": 6e-4, | ||
"wd": 0.0, | ||
"lr_pos_emb": 0.0 | ||
} | ||
): | ||
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# model specific parameters | ||
self.model_map = { | ||
"hyenadna-tiny-1k-seqlen": { | ||
'd_model': 128, | ||
'd_inner': 512, | ||
}, | ||
"hyenadna-tiny-1k-seqlen-d256": { | ||
'd_model': 256, | ||
'd_inner': 1024, | ||
} | ||
} | ||
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if model_name not in self.model_map: | ||
raise ValueError(f"Model name {model_name} not found in available models: {self.model_map.keys()}") | ||
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self.config = { | ||
"model_name": model_name, | ||
"d_model": self.model_map[model_name]['d_model'], | ||
"n_layer": n_layer, | ||
"d_inner": self.model_map[model_name]['d_inner'], | ||
"vocab_size": vocab_size, | ||
"resid_dropout": resid_dropout, | ||
"embed_dropout": embed_dropout, | ||
"fused_mlp": fused_mlp, | ||
"fused_dropout_add_ln": fused_dropout_add_ln, | ||
"residual_in_fp32": residual_in_fp32, | ||
"pad_vocab_size_multiple": pad_vocab_size_multiple, | ||
"return_hidden_state": return_hidden_state, | ||
"layer": layer | ||
} | ||
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import logging | ||
import numpy as np | ||
from anndata import AnnData | ||
from torch.utils.data import DataLoader | ||
import os | ||
from pathlib import Path | ||
from helical.models.hyena_dna.hyena_dna_config import HyenaDNAConfig | ||
from helical.models.helical import HelicalBaseModel | ||
from helical.models.uce.uce_utils import get_ESM2_embeddings, load_model, process_data, get_gene_embeddings | ||
from accelerate import Accelerator | ||
from helical.services.downloader import Downloader | ||
from typing import Optional | ||
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class HyenaDNA(HelicalBaseModel): | ||
"""HyenaDNA model.""" | ||
default_config = HyenaDNAConfig() | ||
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def __init__(self, model_dir: Optional[str] = None, model_config: HyenaDNAConfig = default_config) -> None: | ||
super().__init__() | ||
self.model_config = model_config.config | ||
self.log = logging.getLogger("Hyena-DNA-Model") | ||
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if model_dir is None: | ||
self.downloader = Downloader() | ||
model_path = f"hyena_dna/{self.model_config['model_name']}.ckpt" | ||
self.downloader.download_via_name(model_path) | ||
self.model_path = Path(os.path.join(self.downloader.CACHE_DIR_HELICAL, model_path)) | ||
else: | ||
self.model_path = Path(os.path.join(model_dir, f"{self.model_config['model_name']}.ckpt")) | ||
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def process_data(self): | ||
pass | ||
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def get_embeddings(self): | ||
pass |