Awesome Clonality

A curated list of awesome resources on clonality and tumor heterogeneity.

Tools and their publications

• ASCAT
• Canopy
• Clomial
• cloneHD
• PhyloWGS
• PurityEst
• PyClone
• qpure
• QuantumClone
• sciClone
• SCITE
• THetA

Reviews

• Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution
• Cancer therapy: an evolved approach
• Visualizing Clonal Evolution in Cancer
• Tumor heterogeneity: Causes and consequences

Studies on clonality

• Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
• Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
• Systematic pan-cancer analysis of tumour purity

Oldies but goldies

• The clonal evolution of tumor cell populations
• Tumor Heterogeneity
• Tumor Heterogeneity and the Biology of Cancer Invasion and Metastasis

Theory

• Reference-free inference of tumor phylogenies from single-cell sequencing data

Data sets

• AML31 from UWash