CMI: HBN

Child Mind Institute: Healthy Brain Network

Healthy Brain Network Data Portal

Description: The Healthy Brain Network (HBN) intends to revolutionize child and adolescent psychiatry by providing the scientific community with a large-scale dataset of 10,000 participants through an open data-sharing model. The aggregated database will bring multimodal brain imaging, genetics, and biological samples together with a standardized deep phenotyping protocol that spans a broad range of clinically relevant psychiatric, behavioral, cognitive, and lifestyle information. Rather than the more common model of focusing on a single disorder, we will include a broad range of disorders to promote the identification of biomarkers capable of differentiating between them. This strategy will also allow scientists to evaluate and refine the boundaries between disorders from a biological perspective. The proposed sample will form the foundations on which future efforts can build longitudinal components to facilitate predictions of risk and outcome.

Citation: Alexander, L. et al. An open resource for transdiagnostic research in pediatric mental health and learning disorders. Scientific Data 4, 170181 (2017).

Raw data: Data-Portal-Project

• S3 Bucket: fcp-indi/data/Projects/HBN

• FS6 derivatives

• BIDS_curated

• CPAC processed

• Func data in bids format:

• HBN/MRI/Site-CBIC/subNDARAC350XUM/func * Rest (2 sessions for some sites) + movie viewing * RU N = 1227; CBIC = 288; CUNY = 25; SI = 343 * BIDS: 1.0.2

• Release 8 and 9 behind

Phenotypic data: Healthy Brain Network

• LORIS instructions

Notes:

• LORIS (vs COINS) is best way to access phenotypic data now
• Initial data quality assessment by site SI > CBIC > RU