CMI: HBN

Child Mind Institute: Healthy Brain Network

Healthy Brain Network Data Portal

Description

The Healthy Brain Network (HBN) intends to revolutionize child and adolescent psychiatry by providing the scientific community with a large-scale dataset of 10,000 participants through an open data-sharing model. The aggregated database will bring multimodal brain imaging, genetics, and biological samples together with a standardized deep phenotyping protocol that spans a broad range of clinically relevant psychiatric, behavioral, cognitive, and lifestyle information. Rather than the more common model of focusing on a single disorder, we will include a broad range of disorders to promote the identification of biomarkers capable of differentiating between them. This strategy will also allow scientists to evaluate and refine the boundaries between disorders from a biological perspective. The proposed sample will form the foundations on which future efforts can build longitudinal components to facilitate predictions of risk and outcome.

Citation

Alexander, L. et al. An open resource for transdiagnostic research in pediatric mental health and learning disorders. Scientific Data 4, 170181 (2017).

Raw data

Data-Portal-Project

• S3 Bucket: fcp-indi/data/Projects/HBN
• FS6 derivatives
• BIDS_curated
• CPAC processed
• Func data in bids format:
• HBN/MRI/Site-CBIC/subNDARAC350XUM/func
  • Rest (2 sessions for some sites) + movie viewing
  • RU N = 1227; CBIC = 288; CUNY = 25; SI = 343
  • BIDS: 1.0.2

Phenotypic data

• Healthy Brain Network
• LORIS instructions

Notes

• LORIS (vs COINS) is best way to access phenotypic data now
• Initial data quality assessment by site SI > CBIC > RU
• MRI\Site-CBIC
  • 288 lines in participants.tsv in derivatives, only mention R3 and R4
  • However, ~1096 raw items
  • 700+ actual derivatives

To-do

• double-check how this was processed, or which derivatives were downloaded
• download release 8
• download release 9