A tool for pulling NIMH RDoC informed transdiagnostic phenotypes from medical documentation.
This code is described in High Throughput Phenotyping for Dimensional Psychopathology in Electronic Health Records. This approach to RDoC symptom estimates conceptually follows that reported in A Clinical Perspective on the Relevance of Research Domain Criteria in Electronic Health Records but with an increased focus on ease of distribution.
This software has been applied in:
- Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records
- Stratifying risk for dementia onset using large-scale electronic health record data: a retrospective cohort study
- Research Domain Criteria scores estimated through natural language processing are associated with risk for suicide and accidental death
- Association between child psychiatric emergency room outcomes and dimensions of psychopathology
This was developed on Python 2.7 and depends only on the standard lib. It accepts standard in, as such:
cat your_document.txt | python2 CQHDimensionalPhenotyper.py
For any serious usage you are likely to want to treat CQHDimensionalPhenotyper.py as a library wrapped in your own project specific batch data handling.