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propofol_spatial_pac

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This package contains code for running the analyses described in:

Stephen, E.P., Hotan, G.C., Pierce, E.T., Harrell, P.G., Walsh, J.L., Brown, E.N., Purdon, P.L. (in submission). Broadband slow-wave modulation in posterior and anterior cortex tracks distinct states of propofol-induced unconsciousness. doi.org/10.1101/712604

To set up the code, run:

git clone https://github.com/emilyps14/propofol_spatial_pac.git
conda env update --file environment.yml

Note that the requirements are driven by MNE-Python, so if you run into installation issues, see their installation instructions.

The scripts 1_single_subject_pipeline.py and 2_across_subjects_pipeline.py regenerate Figures 1-4 in the manuscript. The required data will be made available online when the manuscript is published. The variable subjects_dir in each of these scripts should point to the folder containing the data, creating the following folder structure:

<subjects_dir>/eeganes07/input/
<subjects_dir>/input/

The code should work as-is if the repository is stored in the same folder, i.e.:

<subjects_dir>/propofol_spatial_pac/

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