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BigBrain is a singular dataset that offers an ultra-high-resolution (20µm) volumetric reconstruction of a sliced and stained post-mortem human brain (Amunts et al. 2013). BigBrainWarp aims to enable integration of BigBrain with neuroimaging and other neurobiological modalities, helping a wide range of neuroscientists to utilise the cytoarchitectural information encoded in BigBrain for multi-scale neuroscientific discovery.

This repository includes:

  • Preprocessed BigBrain features (direct download from https://fz-juelich.sciebo.de/s/pFu9XfNonT65HpS/download)
  • Simple scripts to transform between BigBrain and standard MRI spaces
  • A selection of histology-derived feature maps already transformed to MRI space, and vice versa
  • A series of tutorials that illustrate potential workflows for BigBrain-MRI integration

See the article (https://elifesciences.org/articles/70119) or readthedocs (https://bigbrainwarp.readthedocs.io/) for all your BigBrainWarp needs

Core developers

  • Casey Paquola, INM-1, Forschungszentrum Jülich & MICA Lab, Montreal Neurological Institute
  • Boris Bernhardt, MICA Lab, Montreal Neurological Institute

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Languages

  • Shell 61.1%
  • MATLAB 25.1%
  • Python 12.0%
  • Dockerfile 1.8%