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Merge pull request #17 from bento-platform/qa/v3.1
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v3.1.2
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brouillette authored Jan 3, 2022
2 parents c2f71a4 + a3ac48b commit 18be6a9
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165 changes: 165 additions & 0 deletions LICENSE
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@@ -0,0 +1,165 @@
GNU LESSER GENERAL PUBLIC LICENSE
Version 3, 29 June 2007

Copyright (C) 2007 Free Software Foundation, Inc. <https://fsf.org/>
Everyone is permitted to copy and distribute verbatim copies
of this license document, but changing it is not allowed.


This version of the GNU Lesser General Public License incorporates
the terms and conditions of version 3 of the GNU General Public
License, supplemented by the additional permissions listed below.

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As used herein, "this License" refers to version 3 of the GNU Lesser
General Public License, and the "GNU GPL" refers to version 3 of the GNU
General Public License.

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other than an Application or a Combined Work as defined below.

An "Application" is any work that makes use of an interface provided
by the Library, but which is not otherwise based on the Library.
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of using an interface provided by the Library.

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Application with the Library. The particular version of the Library
with which the Combined Work was made is also called the "Linked
Version".

The "Minimal Corresponding Source" for a Combined Work means the
Corresponding Source for the Combined Work, excluding any source code
for portions of the Combined Work that, considered in isolation, are
based on the Application, and not on the Linked Version.

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and utility programs needed for reproducing the Combined Work from the
Application, but excluding the System Libraries of the Combined Work.

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The object code form of an Application may incorporate material from
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You may place library facilities that are a work based on the
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is a work based on the Library, and explaining where to find the
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6. Revised Versions of the GNU Lesser General Public License.

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2 changes: 1 addition & 1 deletion Makefile
Original file line number Diff line number Diff line change
Expand Up @@ -114,7 +114,7 @@ stop-%:


# Clean up
clean-all: clean-api clean-api-alpine clean-gateway clean-drs
clean-all: clean-api clean-gateway clean-drs

clean-gateway:
docker rm ${GOHAN_GATEWAY_CONTAINER_NAME} --force; \
Expand Down
1 change: 1 addition & 0 deletions etc/example.env
Original file line number Diff line number Diff line change
Expand Up @@ -47,6 +47,7 @@ GOHAN_API_CONTAINERIZED_VCF_PATH=/app/vcfs
GOHAN_API_GTF_PATH=/path/to/gtfs/on/host/machine
GOHAN_API_CONTAINERIZED_GTF_PATH=/app/gtfs

GOHAN_API_BULK_INDEXING_CAP=10000
GOHAN_API_FILE_PROC_CONC_LVL=3
GOHAN_API_LINE_PROC_CONC_LVL=1000

Expand Down
4 changes: 4 additions & 0 deletions src/api/main.go
Original file line number Diff line number Diff line change
Expand Up @@ -35,6 +35,7 @@ func main() {

"\tVCF Directory Path : %s \n"+
"\tGTF Directory Path : %s \n"+
"\tBulk Indexing Cap : %d\n"+
"\tFile Processing Concurrency Level : %d\n"+
"\tLine Processing Concurrency Level : %d\n"+
"\tElasticsearch Url : %s \n"+
Expand All @@ -55,6 +56,7 @@ func main() {
cfg.Debug,
cfg.Api.VcfPath,
cfg.Api.GtfPath,
cfg.Api.BulkIndexingCap,
cfg.Api.FileProcessingConcurrencyLevel,
cfg.Api.LineProcessingConcurrencyLevel,
cfg.Elasticsearch.Url, cfg.Elasticsearch.Username,
Expand Down Expand Up @@ -169,6 +171,7 @@ func main() {
// middleware
gam.MandateAssemblyIdAttribute)
e.GET("/variants/ingestion/requests", mvc.GetAllVariantIngestionRequests)
e.GET("/variants/ingestion/stats", mvc.VariantsIngestionStats)

// -- Genes
e.GET("/genes/overview", mvc.GetGenesOverview)
Expand All @@ -177,6 +180,7 @@ func main() {
gam.ValidateOptionalChromosomeAttribute)
e.GET("/genes/ingestion/requests", mvc.GetAllGeneIngestionRequests)
e.GET("/genes/ingestion/run", mvc.GenesIngest)
e.GET("/genes/ingestion/stats", mvc.VariantsIngestionStats)

// -- Workflows
e.GET("/workflows", mvc.WorkflowsGet)
Expand Down
1 change: 1 addition & 0 deletions src/api/models/config.go
Original file line number Diff line number Diff line change
Expand Up @@ -8,6 +8,7 @@ type Config struct {
Port string `yaml:"port" envconfig:"GOHAN_API_INTERNAL_PORT"`
VcfPath string `yaml:"vcfPath" envconfig:"GOHAN_API_VCF_PATH"`
LocalVcfPath string `yaml:"localVcfPath" envconfig:"GOHAN_API_VCF_PATH"`
BulkIndexingCap int `yaml:"BulkIndexingCap" envconfig:"GOHAN_API_BULK_INDEXING_CAP"`
FileProcessingConcurrencyLevel int `yaml:"fileProcessingConcurrencyLevel" envconfig:"GOHAN_API_FILE_PROC_CONC_LVL"`
LineProcessingConcurrencyLevel int `yaml:"lineProcessingConcurrencyLevel" envconfig:"GOHAN_API_LINE_PROC_CONC_LVL"`
GtfPath string `yaml:"gtfPath" envconfig:"GOHAN_API_GTF_PATH"`
Expand Down
4 changes: 4 additions & 0 deletions src/api/models/dtos.go
Original file line number Diff line number Diff line change
Expand Up @@ -17,6 +17,8 @@ type BentoV2CompatibleVariantResponseDataModel struct {
GenotypeType string `json:"genotype_type"`
}

// --

type VariantsResponseDTO struct {
Status int `json:"status"`
Message string `json:"message"`
Expand All @@ -29,6 +31,8 @@ type VariantResponseDataModel struct {
Results interface{} `json:"results"` // i.e.: []Variant or []string
}

// -- --

type GenesResponseDTO struct {
Status int `json:"status"`
Message string `json:"message"`
Expand Down
7 changes: 7 additions & 0 deletions src/api/mvc/genes.go
Original file line number Diff line number Diff line change
Expand Up @@ -26,6 +26,13 @@ import (
"github.com/mitchellh/mapstructure"
)

func GenesIngestionStats(c echo.Context) error {
fmt.Printf("[%s] - GenesIngestionStats hit!\n", time.Now())
ingestionService := c.(*contexts.GohanContext).IngestionService

return c.JSON(http.StatusOK, ingestionService.GeneIngestionBulkIndexer.Stats())
}

func GenesIngest(c echo.Context) error {
fmt.Printf("[%s] - GenesIngest hit!\n", time.Now())
// trigger global ingestion background process
Expand Down
17 changes: 17 additions & 0 deletions src/api/mvc/variants.go
Original file line number Diff line number Diff line change
Expand Up @@ -32,6 +32,13 @@ import (
"github.com/mitchellh/mapstructure"
)

func VariantsIngestionStats(c echo.Context) error {
fmt.Printf("[%s] - VariantsIngestionStats hit!\n", time.Now())
ingestionService := c.(*contexts.GohanContext).IngestionService

return c.JSON(http.StatusOK, ingestionService.IngestionBulkIndexer.Stats())
}

func VariantsGetByVariantId(c echo.Context) error {
fmt.Printf("[%s] - VariantsGetByVariantId hit!\n", time.Now())
// retrieve variant Ids from query parameter (comma separated)
Expand Down Expand Up @@ -226,11 +233,13 @@ func VariantsIngest(c echo.Context) error {
// free up a spot in the queue
defer func() { <-ingestionService.ConcurrentFileIngestionQueue }()

fmt.Printf("Begin running %s !\n", gzippedFileName)
reqStat.State = ingest.Running
ingestionService.IngestRequestChan <- reqStat

// --- decompress vcf.gz

fmt.Printf("Decompressing %s !\n", gzippedFileName)
gzippedFilePath := fmt.Sprintf("%s%s", vcfPath, gzippedFileName)
r, err := os.Open(gzippedFilePath)
if err != nil {
Expand Down Expand Up @@ -286,6 +295,7 @@ func VariantsIngest(c echo.Context) error {
// -----

// --- tabix generation
fmt.Printf("Generating Tabix %s !\n", tmpDestinationFileName)
tabixFileDir, tabixFileName, tabixErr := ingestionService.GenerateTabix(tmpDestinationFileName)
if tabixErr != nil {
msg := "Something went wrong: Tabix problem " + gzippedFileName
Expand All @@ -300,6 +310,7 @@ func VariantsIngest(c echo.Context) error {
tabixFileNameWithRelativePath := fmt.Sprintf("%s%s", partialTmpDir, tabixFileName)

// --- push compressed to DRS
fmt.Printf("Uploading %s to DRS !\n", gzippedFileName)
drsFileId := ingestionService.UploadVcfGzToDrs(cfg.Drs.BridgeDirectory, gzippedFileName, drsUrl, drsUsername, drsPassword)
if drsFileId == "" {
msg := "Something went wrong: DRS File Id is empty for " + gzippedFileName
Expand All @@ -313,6 +324,7 @@ func VariantsIngest(c echo.Context) error {
}

// -- push tabix to DRS
fmt.Printf("Uploading %s to DRS !\n", tabixFileNameWithRelativePath)
drsTabixFileId := ingestionService.UploadVcfGzToDrs(cfg.Drs.BridgeDirectory, tabixFileNameWithRelativePath, drsUrl, drsUsername, drsPassword)
if drsTabixFileId == "" {
msg := "Something went wrong: DRS Tabix File Id is empty for " + tabixFileNameWithRelativePath
Expand All @@ -326,6 +338,7 @@ func VariantsIngest(c echo.Context) error {
}

// --- remove temporary files now that they have been ingested successfully into DRS
fmt.Printf("Removing %s !\n", tmpDestinationFileName)
if tmpFileRemovalErr := os.Remove(tmpDestinationFileName); tmpFileRemovalErr != nil {
msg := fmt.Sprintf("Something went wrong: trying to remove temporary file at %s : %s\n", tmpDestinationFileName, tmpFileRemovalErr)
fmt.Println(msg)
Expand All @@ -337,6 +350,7 @@ func VariantsIngest(c echo.Context) error {
return
}
tmpTabixFilePath := fmt.Sprintf("%s%s", tabixFileDir, tabixFileName)
fmt.Printf("Removing %s !\n", tmpTabixFilePath)
if tmpTabixFileRemovalErr := os.Remove(tmpTabixFilePath); tmpTabixFileRemovalErr != nil {
msg := fmt.Sprintf("Something went wrong: trying to remove temporary file at %s : %s\n", tmpTabixFilePath, tmpTabixFileRemovalErr)
fmt.Println(msg)
Expand Down Expand Up @@ -374,6 +388,7 @@ func VariantsIngest(c echo.Context) error {
}

// --- extract gzip compressed vcf file
fmt.Printf("Extracting %s !\n", gzippedFilePath)
vcfFilePath := ingestionService.ExtractVcfGz(gzippedFilePath, r, vcfTmpPath)
if vcfFilePath == "" {
msg := "Something went wrong: filepath is empty for " + gzippedFileName
Expand All @@ -388,9 +403,11 @@ func VariantsIngest(c echo.Context) error {
defer r.Close()

// --- load vcf into memory and ingest the vcf file into elasticsearch
fmt.Printf("Begin processing %s !\n", vcfFilePath)
ingestionService.ProcessVcf(vcfFilePath, drsFileId, assemblyId, filterOutHomozygousReferences, cfg.Api.LineProcessingConcurrencyLevel)

// --- delete the temporary vcf file
fmt.Printf("Removing temporary file %s !\n", vcfFilePath)
os.Remove(vcfFilePath)

// --- delete full tmp path and all contents
Expand Down
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