Allele ages provide limited information about the strength of negative selection

This repository contains code for the models developed in this manuscript: https://doi.org/10.1101/2024.08.06.606888.

manual.ipynb (this is all that you'll need)

notebook containing explanatory code for using the functions below

mom_functions.py

script containing the necessary source code

PReFerSims/

folder containing the (somewhat) elaborate machinery required for the simulations in the manuscript (PReFerSim -> mssel -> Relate -> moments)

figs/

folder containing figures for the manuscript

archive/

folder containing old tensorflow code for computing the distribution of allele ages conditional on frequency

Contact Vivaswat for questions with running any of the code in this repo.