Woodstock
First release of WISECONDOR.
Changes since pre-release version (wisecondor_130517_DB):
- Fixed: Missing imports for python2.6
- Fixed: Wrong value in AAD computation
- Fixed: Faulty removal of 'chr' prefix in consam.py when no prefix is present
- Changed: Default backend for matplotlib, now using 'agg'
- Changed: Plotting moved to separate script (plot.py)
- Removed: Useless, no longer supported qc scripts
- Several improvements in argument usage explanations
Please note:
Although the paper describes certain steps using SOAP2, this release uses BWA as mapper and converts from BAM files accordingly. If you want to use SOAP2 instead, please check the argument options for consam.py and add the appropriate columns for the needed information.
Also, the fix for the AAD computation changes the AAD results slightly: although removing a mistake, the paper does not reflect the actual computation anymore. In the paper and previous versions, the tested bin value was used to determine the relative change in read depth while this should be based on the values in the reference set, thus removing influences of aberrations. Changes in the AAD results should range from 0.001% to 0.01%, making the effect negligible.