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Human 1.19 deprecated since this does not follow the guidelines #819
Commits on May 21, 2023
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fix: Fixed a bug in importYaml.m for when you have an old MATLAB vers…
…ion. I don't think that code had ever been run, it was just not right.
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feat: Added gene essentiality prediction from DepMap data. The code c…
…urrently only processes the model available in the repo, and does not compare with any older model version. The code is however prepared for comparing versions. Currently, it only processes 2 out of 40 chunks of data, this is to be changed when we want to run a full evaluation with 891 cell lines.
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Commits on May 22, 2023
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Update code/DepMapGeneEss/Instructions.txt
Co-authored-by: Mihail Anton <[email protected]>
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Update code/DepMapGeneEss/PrepDepMapData.m
Co-authored-by: Mihail Anton <[email protected]>
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Update code/DepMapGeneEss/enrichment_test.m
Co-authored-by: Mihail Anton <[email protected]>
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Commits on May 24, 2023
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Update code/DepMapGeneEss/ConvertGeneEssInputData.R
Co-authored-by: Mihail Anton <[email protected]>
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Update code/DepMapGeneEss/PlotGeneEss.R
Co-authored-by: Mihail Anton <[email protected]>
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Commits on Jul 6, 2023
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Commits on Nov 23, 2023
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Feat: create metabolites_SMILES_inchi.tsv
Added metabolite SMILES and Inchi Information
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Commits on Dec 6, 2023
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fix: remove MAR03748 and MAR03780 and merge annotations in reactions.…
…tsv into MAR06416/7 and MAR06419/20
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Commits on Dec 8, 2023
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fix: update GPRs of MAR06416, MAR06419, MAR06421, and MAR06523 and re…
…move TMEM91 from the model
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fix: remove MAR06329 for being redundant with MAR03149 + MAR03150 + M…
…AR03151 + MAR03153
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fix: remove MAR06283 for being redundant with MAR03156 + MAR03157 + M…
…AR03158 + MAR03160
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fix: remove MAR05449 for being redundant with MAR03163 + MAR03164 + M…
…AR03166 + MAR03885
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fix: remove MAR01009 for being redundant with MAR03885 and MAR03149,5…
…0,51,53,56,57,58,60,63,64,66
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Commits on Dec 9, 2023
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Commits on Dec 10, 2023
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feat: added thiamine-dependent decarboxylation reactions for BCKDH an…
…d 2-OADH reactions and thiamine-to-lipoyl transfer for 2-OADH
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fix: adjusted existing BCKDH and 2-OADH reactions to connect to new t…
…hiamine-dependent steps
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Merge pull request #743 from SysBioChalmers/fix/BCKDH_duplicates
Fix Duplicate BCKDH Reactions
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Merge pull request #752 from SysBioChalmers/fix/remove_MAR03422
Remove MAR03422
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Commits on Dec 13, 2023
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fix: remove MAR03426 and merge annotations in reactions.tsv with reac…
…tions it duplicated
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Merge pull request #760 from SysBioChalmers/fix/MAR03269_MAR03380
Fix GPRs for MAR03269 and MAR03380
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Commits on Dec 14, 2023
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fix: merged in latest develop branch and corrected weird annotation i…
…nconsistencies in reactions.tsv
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fix-GPR: remove ENSG00000113790 from GPRs of b-oxidation rxns in mito
- remove ENSG00000113790 from GPRs of MAR03297, MAR03374, MAR03378, MAR03379
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Commits on Dec 16, 2023
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Commits on Dec 18, 2023
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Merge pull request #750 from SysBioChalmers/fix/BCKDH_genes
Fix BCKDH Genes and Remove Mito & Nuc Thiocyanate <-> Hypothiocyanite Reactions
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Merge pull request #768 from SysBioChalmers/fix/linolenoyl_beta_oxida…
…tion Remove Duplicate Linolenoyl-CoA Beta-Oxidation Reactions
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Merge pull request #770 from SysBioChalmers/removePeroGenesFromBetaox…
…idationGPRsInMito fix: remove genes only expressed in peroxisome from beta-oxidation reactions in mitochondria
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Commits on Dec 22, 2023
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Commits on Dec 23, 2023
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Merge pull request #751 from SysBioChalmers/fix/octanoyl_beta_ox_dupes
Fix Duplicate Octanoyl-CoA Beta-Oxidation Reactions
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Commits on Dec 26, 2023
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fix-gpr: remove DECR2 from mitochondria beta-oxidation reactions
set GPRs of MAR01176, MAR01181, MAR01218, MAR01222, MAR MAR03446, and MAR03457 to ENSG00000104325
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fix-gpr: remove DECR1 from peroxisome beta-oxidation reactions
Set the GPRs of MAR01297, MAR03461, and MAR03471 to ENSG00000242612
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Commits on Dec 27, 2023
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Merge pull request #788 from SysBioChalmers/fix/DECR1DECR2_rxnsGPRs
fix: revise rxns and GPRs associated with DECR1 and DECR2
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Merge pull request #789 from SysBioChalmers/fix/decanoyl_beta_ox_dupes
Remove Duplicate Decanoyl-CoA to Octanoyl-CoA Beta-Oxidation Reactions
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Commits on Dec 28, 2023
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Commits on Dec 31, 2023
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Commits on Jan 2, 2024
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Merge pull request #790 from SysBioChalmers/fix/MAR03288_GPR
Remove EHHADH from the GPR of MAR03288
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Commits on Jan 4, 2024
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Commits on Jan 8, 2024
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Merge pull request #753 from SysBioChalmers/fix/thiamine_in_oxoacid_d…
…ehydrogenase_rxns Fix inconsistent representation of thiamine and lipoic acid in 2-oxoacid dehydrogenase reactions
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Merge pull request #794 from SysBioChalmers/fix/remove_MAR00965
Remove MAR00965 and Fix GPR of MAR00970
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Commits on Jan 10, 2024
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Merge pull request #731 from JHL-452b/feat_smiles_inchi
Feat: added smiles and inchi of metabolites
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Commits on Jan 11, 2024
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Merge pull request #803 from SysBioChalmers/chore/pmid-typos
chore: pmid typos
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Commits on Jan 28, 2024
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fix: brought back previously-deprecated MAM03884 metabolites and rena…
…med to (3S)-phytanic acid
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fix: brought back previously-deprecated MAM00077x and MAR03488 and re…
…placed MAM00564x with MAM20083x in MAR03488
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fix: renamed MAM02766 metabolites to (2S)-pristanic acid (wrongly ren…
…amed them to (3S)-pristanic acid in earlier commit)
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feat: created MAR20179 and MAR20180 to represent export and exchange …
…of (2R)-pristanic acid
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chore: moved row for MAM02955c from model/metabolites.tsv to data/dep…
…recatedIdentifiers/deprecatedMetabolties.tsv
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chore: moved rows for MAR04774 and MAR04775 from model/reactions.tsv …
…to data/deprecatedIdentifiers/deprecatedReactions.tsv
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Commits on Mar 13, 2024
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Commits on Mar 19, 2024
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Merge pull request #811 from SysBioChalmers/fix/exchangeRxnNames
fix: standardize all names of exchange reactions
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Commits on Apr 4, 2024
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Commits on Apr 23, 2024
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Merge pull request #574 from SysBioChalmers/feat/AddGeneEssDepMap
feat: add gene essentiality check using DepMap
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Merge pull request #792 from SysBioChalmers/fix/phytanoyl_alpha_ox
Resolve Duplicate Phytanoyl-CoA Alpha-Oxidation Reactions
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Merge pull request #793 from SysBioChalmers/fix/dupe_linoleoyl_gamma_…
…linolenoyl_beta_ox_paths Merge Duplicate Mitochondrial Linoleic and Gamma-Linolenic Acid Beta-Oxidation Pathways
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Commits on Apr 24, 2024
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Merge pull request #808 from SysBioChalmers/fix/remove_EHHADH_from_mi…
…to_gprs fix: GPRs for mitochondrial 2-enoyl-CoA hydratase reactions
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Merge pull request #807 from SysBioChalmers/fix/tagatose
Remove Tagatose-1,6-Bisphosphate
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Merge pull request #805 from SysBioChalmers/fix/phytanic_stereo
Fix Stereochemistry of Phytanic Acid Oxidation
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Commits on Apr 25, 2024
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Commits on Apr 26, 2024
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Merge pull request #816 from JHL-452b/fix-Correction_of_unbalanced_re…
…actions fix: modified unbalance reactions
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Commits on May 6, 2024
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Merge pull request #815 from SysBioChalmers/fix/thiamine_transport
Fix Mitochondrial Thiamine Transport Reactions
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Commits on May 7, 2024
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Merge pull request #818 from SysBioChalmers/chore/update-actions
chore: update actions
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