feat: added new genes to YAML file and genes.tsv for all genes in new…

… reactions not already present
SysBioChalmers · Jun 20, 2024 · 7bf6a63 · 7bf6a63
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diff --git a/model/Human-GEM.yml b/model/Human-GEM.yml
@@ -306164,6 +306164,9 @@
     - !!omap
       - id: "ENSG00000100197"
       - name: "CYP2D6"
+    - !!omap
+      - id: "ENSG00000100209"
+      - name: "HSCB"
     - !!omap
       - id: "ENSG00000100243"
       - name: "CYB5R3"
@@ -306689,6 +306692,9 @@
     - !!omap
       - id: "ENSG00000105701"
       - name: "FKBP8"
+    - !!omap
+      - id: "ENSG00000105755"
+      - name: "ETHE1"
     - !!omap
       - id: "ENSG00000105835"
       - name: "NAMPT"
@@ -306920,6 +306926,9 @@
     - !!omap
       - id: "ENSG00000109452"
       - name: "INPP4B"
+    - !!omap
+      - id: "ENSG00000109519"
+      - name: "GRPEL1"
     - !!omap
       - id: "ENSG00000109576"
       - name: "AADAT"
@@ -307208,6 +307217,9 @@
     - !!omap
       - id: "ENSG00000112992"
       - name: "NNT"
+    - !!omap
+      - id: "ENSG00000113013"
+      - name: "HSPA9"
     - !!omap
       - id: "ENSG00000113073"
       - name: "SLC4A9"
@@ -308618,6 +308630,9 @@
     - !!omap
       - id: "ENSG00000135069"
       - name: "PSAT1"
+    - !!omap
+      - id: "ENSG00000135070"
+      - name: "ISCA1"
     - !!omap
       - id: "ENSG00000135093"
       - name: "USP30"
@@ -308699,6 +308714,9 @@
     - !!omap
       - id: "ENSG00000135940"
       - name: "COX5B"
+    - !!omap
+      - id: "ENSG00000136003"
+      - name: "ISCU"
     - !!omap
       - id: "ENSG00000136010"
       - name: "ALDH1L2"
@@ -308840,9 +308858,15 @@
     - !!omap
       - id: "ENSG00000137563"
       - name: "GGH"
+    - !!omap
+      - id: "ENSG00000137714"
+      - name: "FDX1"
     - !!omap
       - id: "ENSG00000137731"
       - name: "FXYD2"
+    - !!omap
+      - id: "ENSG00000137767"
+      - name: "SQOR"
     - !!omap
       - id: "ENSG00000137770"
       - name: "CTDSPL2"
@@ -310904,6 +310928,9 @@
     - !!omap
       - id: "ENSG00000165841"
       - name: "CYP2C19"
+    - !!omap
+      - id: "ENSG00000165898"
+      - name: "ISCA2"
     - !!omap
       - id: "ENSG00000165970"
       - name: "SLC6A5"
@@ -311300,6 +311327,9 @@
     - !!omap
       - id: "ENSG00000169432"
       - name: "SCN9A"
+    - !!omap
+      - id: "ENSG00000169599"
+      - name: "NFU1"
     - !!omap
       - id: "ENSG00000169660"
       - name: "HEXD"
@@ -312143,6 +312173,9 @@
     - !!omap
       - id: "ENSG00000181867"
       - name: "FTMT"
+    - !!omap
+      - id: "ENSG00000181873"
+      - name: "IBA57"
     - !!omap
       - id: "ENSG00000181915"
       - name: "ADO"
@@ -312182,6 +312215,9 @@
     - !!omap
       - id: "ENSG00000182415"
       - name: "CDY2A"
+    - !!omap
+      - id: "ENSG00000182512"
+      - name: "GLRX5"
     - !!omap
       - id: "ENSG00000182551"
       - name: "ADI1"
@@ -313325,6 +313361,9 @@
     - !!omap
       - id: "ENSG00000243989"
       - name: "ACY1"
+    - !!omap
+      - id: "ENSG00000244005"
+      - name: "NFS1"
     - !!omap
       - id: "ENSG00000244038"
       - name: "DDOST"
@@ -313430,6 +313469,9 @@
     - !!omap
       - id: "ENSG00000266200"
       - name: "PNLIPRP2"
+    - !!omap
+      - id: "ENSG00000267673"
+      - name: "FDX2"
     - !!omap
       - id: "ENSG00000267855"
       - name: "NDUFA7"

diff --git a/model/genes.tsv b/model/genes.tsv
@@ -2886,3 +2886,17 @@ genes	geneENSTID	geneENSPID	geneUniProtID	geneSymbols	geneEntrezID	geneNames	gen
 "ENSG00000196407"	"ENST00000368817.10;ENST00000453881.2"	"ENSP00000357807.4;ENSP00000406809.2"	"Q8N1Q8"	"THEM5"	"284486"	"thioesterase superfamily member 5"	"ACOT15"	"Inner mitochondria"	"SwissProt"
 "ENSG00000013306"	"ENST00000377095;ENST00000225308;ENST00000590194;ENST00000537904;ENST00000586016;ENST00000588049;ENST00000592857;ENST00000588767;ENST00000585523;ENST00000586633;ENST00000585636;ENST00000593166;ENST00000591006;ENST00000588315;ENST00000585695;ENST00000592372;ENST00000591151"	"ENSP00000366299;ENSP00000225308;ENSP00000467681;ENSP00000444540;ENSP00000466676;ENSP00000465182;ENSP00000467956;ENSP00000466615;ENSP00000466144;ENSP00000465594;ENSP00000465554"	"Q9BZJ4"	"SLC25A39"	"51629"	"solute carrier family 25 member 39"	""	""	""
 "ENSG00000075303"	"ENST00000341119;ENST00000429674;ENST00000444363;ENST00000446236;ENST00000470328;ENST00000483810;ENST00000491499;ENST00000496348"	"ENSP00000344831;ENSP00000401473;ENSP00000405566;ENSP00000407780"	"Q8TBP6"	"SLC25A40"	"55972"	"solute carrier family 25 member 40"	"MCFP"	""	""
+"ENSG00000100209"	"ENST00000216027.8;ENST00000398941.6"	"ENSP00000216027.3;ENSP00000381914.2"	"Q8IWL3"	"HSCB"	"150274"	"HscB mitochondrial iron-sulfur cluster cochaperone"	""	""	""
+"ENSG00000105755"	"ENST00000292147.7;ENST00000600651.5"	"ENSP00000292147.1;ENSP00000469037.1"	"O95571"	"ETHE1"	"23474"	"ETHE1 persulfide dioxygenase"	""	""	""
+"ENSG00000109519"	"ENST00000264954.5;ENST00000706689.1"	"ENSP00000264954.4;ENSP00000516503.1"	"Q9HAV7"	"GRPEL1"	"80273"	"GrpE like 1, mitochondrial"	""	""	""
+"ENSG00000113013"	"ENST00000297185.9;ENST00000677066.1;ENST00000678300.1;ENST00000678384.1;ENST00000678051.1;ENST00000677425.1;ENST00000677064.1;ENST00000507115.6"	"ENSP00000297185.3;ENSP00000502902.1;ENSP00000503259.1;ENSP00000503992.1;ENSP00000503219.1;ENSP00000503066.1;ENSP00000503373.1;ENSP00000423759.2"	"P38646"	"HSPA9"	"3313"	"heat shock protein family A (Hsp70) member 9"	""	""	""
+"ENSG00000135070"	"ENST00000375991.9;ENST00000326094.4;ENST00000311534.6;ENST00000637705.1"	"Q9BUE6"	"ISCA1"	"81689"	"iron-sulfur cluster assembly 1"	""	""	""
+"ENSG00000136003"	"ENST00000311893.14;ENST00000535729.5;ENST00000539593.1;ENST00000392807.8;ENST00000431221.6;ENST00000547005.5"	"ENSP00000310623.9;ENSP00000445598.1;ENSP00000443272.1;ENSP00000376554.4;ENSP00000411108.2;ENSP00000446606.1"	"Q9H1K1"	"ISCU"	"23479"	"iron-sulfur cluster assembly enzyme"	""	""	""
+"ENSG00000137714"	"ENST00000260270.3"	"ENSP00000260270.2"	"P10109"	"FDX1"	"2230"	"ferredoxin 1"
+"ENSG00000137767"	"ENST00000260324.12;ENST00000568606.5;ENST00000566934.1;ENST00000561735.5;ENST00000561493.5;ENST00000563296.1;ENST00000565997.1;ENST00000565227.1"	"ENSP00000260324.7;ENSP00000456019.1;ENSP00000454520.1;ENSP00000456075.1;ENSP00000457937.1;ENSP00000456979.1;ENSP00000454953.1;ENSP00000457592.1"	"Q9Y6N5"	"SQOR"	"58472"	"sulfide quinone oxidoreductase"	""	""	""
+"ENSG00000165898"	"ENST00000556816.6;ENST00000298818.12;ENST00000554924.1"	"ENSP00000452007.1;ENSP00000298818.8;ENSP00000450523.1"	"Q86U28"	"ISCA2"	"122961"	"iron-sulfur cluster assembly 2"	""	""	""
+"ENSG00000169599"	"ENST00000410022.7;ENST00000394305.5;ENST00000303698.7;ENST00000484177.5;ENST00000450796.6;ENST00000462320.5"	"ENSP00000387219.3;ENSP00000377842.1;ENSP00000306965.3;ENSP00000417693.1;ENSP00000415102.2;ENSP00000418598.1"	"Q9UMS0"	"NFU1"	"27247"	"NFU1 iron-sulfur cluster scaffold"	""	""	""
+"ENSG00000181873"	"ENST00000366711.4"	"ENSP00000355672.3"	"Q5T440"	"IBA57"	"200205"	"iron-sulfur cluster assembly factor IBA57"	""	""	""
+"ENSG00000182512"	"ENST00000331334.5;ENST00000557731.1"	"ENSP00000328570.4;ENSP00000451800.1"	"Q86SX6"	"GLRX5"	"51218"	"glutaredoxin 5"	""	""	""
+"ENSG00000244005"	"ENST00000374092.9;ENST00000374085.5;ENST00000397425.5;ENST00000541387.5;ENST00000306750.3;ENST00000419569.5"	"ENSP00000363205.3;ENSP00000363198.1;ENSP00000380570.1;ENSP00000440897.1;ENSP00000304740.3;ENSP00000393482.1"	"Q9Y697"	"NFS1"	"9054"	"NFS1 cysteine desulfurase"	""	""	""
+"ENSG00000267673"	"ENST00000393708.3;ENST00000492239.5;ENST00000494368.5;ENST00000706663.1"	"ENSP00000377311.5;ENSP00000488228.1;ENSP00000467188.1;ENSP00000516489.1"	"Q6P4F2"	"FDX2"	"112812"	"ferredoxin 2"	""	""	""