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DESCRIPTION
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DESCRIPTION
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Package: edmr
Type: Package
Title: Empirical Differentially Methylated Regions Calculation
Description: Optimized DMR analysis based on bimodal normal distribution
model and cost function for regional methylation analysis optimization.
It captures the regional methylation modification by taking the spatial
distribution of CpGs into account for the enrichment DNA methylation sequencing
data so as to optimize the definition of the empirical regions. Combined with
the dependent adjustment for regional p-value combination and DMR annotation.
Version: 0.6.4.1
Authors@R: c(person(given="Sheng", family="Li", role=c("aut","cre", "cph"), email = "[email protected]"),
person(given="Francine", family="Garrett-Bakelman", role="ctb"),
person(family="Akalin", given="Altuna", role="ctb"),
person(family="Zumbo", given="Paul", role="ctb"),
person(family="Melnick", given="Ari", role="ctb"),
person(family="Mason", given="Chris", role=c("ctb","ths")))
Maintainer: Sheng Li <[email protected]>
Depends: R (>= 3.2.0)
Imports: GenomicRanges, IRanges, data.table, mixtools, S4Vectors
License: Artistic-2.0
URL: https://github.com/ShengLi/edmr
LazyData: true
Collate: 'ACF.R' 'edmr.R' 'eDMR.sub.R' 'get.dist.cutoff.R' 'getDMR.R'
'getPeaks.R' 'helpers.R' 'myDiff.to.mixmdl.R' 'myDiffToDMR.R'
'plotCost.R' 'plotMdl1.R' 'filter.dmr.R' 'annotation.R'
'document_data.R'
Packaged: 2016-05-01 00:38:10 EST; shl2018
Author: Sheng Li [aut, cre, cph],
Francine Garrett-Bakelman [ctb],
Altuna Akalin [ctb],
Paul Zumbo [ctb],
Ari Melnick [ctb],
Chris Mason [ctb, ths]
NeedsCompilation: no
Repository: CRAN
Date/Publication: 2016-05-01