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| <!DOCTYPE html> <html lang="en"> <head> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8"> <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <title> Nolan & Sürmeli Lab </title> <meta name="author" content="Nolan & Sürmeli"> <meta name="description" content="The Nolan x Surmelli Lab website. "> <meta name="keywords" content="jekyll, jekyll-theme, academic-website, portfolio-website"> <link rel="stylesheet" href="/assets/css/bootstrap.min.css?a4b3f509e79c54a512b890d73235ef04"> <link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/[email protected]/css/mdb.min.css" integrity="sha256-jpjYvU3G3N6nrrBwXJoVEYI/0zw8htfFnhT9ljN3JJw=" crossorigin="anonymous"> <link defer rel="stylesheet" href="/assets/css/academicons.min.css?f0b7046b84e425c55f3463ac249818f5"> <link defer rel="stylesheet" type="text/css" href="https://fonts.googleapis.com/css?family=Roboto:300,400,500,700|Roboto+Slab:100,300,400,500,700|Material+Icons&display=swap"> <link defer rel="stylesheet" href="/assets/css/jekyll-pygments-themes-github.css?591dab5a4e56573bf4ef7fd332894c99" media="" id="highlight_theme_light"> <link rel="shortcut icon" href="data:image/svg+xml,<svg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%20100%20100%22><text%20y=%22.9em%22%20font-size=%2290%22>%F0%9F%A7%A0</text></svg>"> <link rel="stylesheet" href="/assets/css/main.css?d41d8cd98f00b204e9800998ecf8427e"> <link rel="canonical" href="https://mattnolanlab.github.io/"> </head> <body class=" sticky-bottom-footer"> <header> <div class="container"> <img src="/assets/img/banner.png" class="banner" alt="Banner Image" style="width: 100%; height: auto;"> </div> <nav id="navbar" class="navbar container navbar-light navbar-expand-sm sticky-top" role="navigation"> <button class="navbar-toggler collapsed ml-auto" type="button" data-toggle="collapse" data-target="#navbarNav" aria-controls="navbarNav" aria-expanded="false" aria-label="Toggle navigation"> <span class="sr-only">Toggle navigation</span> <span class="icon-bar top-bar"></span> <span class="icon-bar middle-bar"></span> <span class="icon-bar bottom-bar"></span> </button> <div class="collapse navbar-collapse text-right" id="navbarNav"> <ul class="navbar-nav ml-auto flex-nowrap"> <li class="nav-item active"> <a class="nav-link" href="/">about <span class="sr-only">(current)</span> </a> </li> <li class="nav-item "> <a class="nav-link" href="/research/">research </a> </li> <li class="nav-item "> <a class="nav-link" href="/manual/">values </a> </li> <li class="nav-item "> <a class="nav-link" href="/values/">values </a> </li> <li class="nav-item "> <a class="nav-link" href="/publications/">publications </a> </li> <li class="nav-item "> <a class="nav-link" href="/repositories/">code & tools </a> </li> <li class="nav-item "> <a class="nav-link" href="/people-nolan/">Nolan group </a> </li> <li class="nav-item "> <a class="nav-link" href="/people-surmeli/">Sürmeli group </a> </li> </ul> </div> </nav> </header> <div class="container mt-5" role="main"> <div class="post"> <article> <div class="clearfix"> <p>We aim to understand the cellular and molecular basis for computations that underlie episodic memory. We are based in the <a href="https://discovery-brain-sciences.ed.ac.uk/" rel="external nofollow noopener" target="_blank">Centre for Discovery Brain Sciences</a> and the <a href="https://sidb.org.uk/" rel="external nofollow noopener" target="_blank">Simons Initative for the Developing Brain</a>. Our research follows four themes:</p> <p><strong>Circuit organisation.</strong> We are investigating the local and long-range organisation of circuits in the entorhinal cortex. We want to understand how molecular level organisation within the entorhinal cortex leads to architectural principles that are critical for memory storage and retrieval.</p> <p><strong>Circuit computations.</strong> We are using high density neural recordings and neural network models to investigate how entorhinal cortex circuits implement computations important for spatial memory.</p> <p><strong>Technology development.</strong> With collaborators in the <a href="https://www.eng.ed.ac.uk/research/institutes/imns/about" rel="external nofollow noopener" target="_blank">Institute for Integrated and Nano Systems</a> we are developing kilohertz frame rate cameras for imaging neural activity, and with collaborators in the <a href="https://web.inf.ed.ac.uk/anc" rel="external nofollow noopener" target="_blank">School of informatics</a> and the <a href="https://centreforstatistics.maths.ed.ac.uk/" rel="external nofollow noopener" target="_blank">Centre for Statistics</a> we are developing new tools for analysing the organisation and activation of neural circuits.</p> <p><strong>Circuit disorders.</strong> Many disorders of the brain appear to result from circuit level deficits. We believe that understanding the fundamental principles for neural circuit computation will be essential for understanding and treating disorders. We are addressing this by focusing on models of autism spectrum disorders and Alzheimer’s disease.</p> </div> <h2> <a href="/news/" style="color: inherit">news</a> </h2> <div class="news"> <div class="table-responsive"> <table class="table table-sm table-borderless"> <tr> <th scope="row" style="width: 20%">Mar 14, 2024</th> <td> We’re building the new website! </td> </tr> <tr> <th scope="row" style="width: 20%">Mar 14, 2024</th> <td> We’re building the new website! Harry’s <a href="https://elifesciences.org/articles/89356" rel="external nofollow noopener" target="_blank">paper</a> investigating grid firing and behaviour is out. A lot of hard work and a very exciting result. Well done Harry! </td> </tr> </table> </div> </div> </article> </div> </div> <footer class="sticky-bottom mt-5" role="contentinfo"> <div class="container"> © Copyright 2024 Nolan & Sürmeli. </div> </footer> <script src="https://cdn.jsdelivr.net/npm/[email protected]/dist/jquery.min.js" integrity="sha256-/xUj+3OJU5yExlq6GSYGSHk7tPXikynS7ogEvDej/m4=" crossorigin="anonymous"></script> <script src="/assets/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.jsdelivr.net/npm/[email protected]/js/mdb.min.js" integrity="sha256-NdbiivsvWt7VYCt6hYNT3h/th9vSTL4EDWeGs5SN3DA=" crossorigin="anonymous"></script> <script defer src="https://cdn.jsdelivr.net/npm/[email protected]/dist/masonry.pkgd.min.js" integrity="sha256-Nn1q/fx0H7SNLZMQ5Hw5JLaTRZp0yILA/FRexe19VdI=" crossorigin="anonymous"></script> <script defer src="https://cdn.jsdelivr.net/npm/[email protected]/imagesloaded.pkgd.min.js" integrity="sha256-htrLFfZJ6v5udOG+3kNLINIKh2gvoKqwEhHYfTTMICc=" crossorigin="anonymous"></script> <script defer src="/assets/js/masonry.js" type="text/javascript"></script> <script defer src="https://cdn.jsdelivr.net/npm/[email protected]/dist/medium-zoom.min.js" integrity="sha256-ZgMyDAIYDYGxbcpJcfUnYwNevG/xi9OHKaR/8GK+jWc=" crossorigin="anonymous"></script> <script defer src="/assets/js/zoom.js?85ddb88934d28b74e78031fd54cf8308"></script> <script src="/assets/js/no_defer.js?2930004b8d7fcd0a8e00fdcfc8fc9f24"></script> <script defer src="/assets/js/common.js?4a129fbf39254905f505c7246e641eaf"></script> <script defer src="/assets/js/copy_code.js?12775fdf7f95e901d7119054556e495f" type="text/javascript"></script> <script async src="https://d1bxh8uas1mnw7.cloudfront.net/assets/embed.js"></script> <script async src="https://badge.dimensions.ai/badge.js"></script> <script type="text/javascript">window.MathJax={tex:{tags:"ams"}};</script> <script defer type="text/javascript" id="MathJax-script" src="https://cdn.jsdelivr.net/npm/[email protected]/es5/tex-mml-chtml.js"></script> <script defer src="https://polyfill.io/v3/polyfill.min.js?features=es6"></script> </body> </html> | ||
| <!DOCTYPE html> <html lang="en"> <head> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8"> <meta charset="utf-8"> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <title> Nolan & Sürmeli Lab </title> <meta name="author" content="Nolan & Sürmeli"> <meta name="description" content="The Nolan x Surmelli Lab website. "> <meta name="keywords" content="jekyll, jekyll-theme, academic-website, portfolio-website"> <link rel="stylesheet" href="/assets/css/bootstrap.min.css?a4b3f509e79c54a512b890d73235ef04"> <link rel="stylesheet" href="https://cdn.jsdelivr.net/npm/[email protected]/css/mdb.min.css" integrity="sha256-jpjYvU3G3N6nrrBwXJoVEYI/0zw8htfFnhT9ljN3JJw=" crossorigin="anonymous"> <link defer rel="stylesheet" href="/assets/css/academicons.min.css?f0b7046b84e425c55f3463ac249818f5"> <link defer rel="stylesheet" type="text/css" href="https://fonts.googleapis.com/css?family=Roboto:300,400,500,700|Roboto+Slab:100,300,400,500,700|Material+Icons&display=swap"> <link defer rel="stylesheet" href="/assets/css/jekyll-pygments-themes-github.css?591dab5a4e56573bf4ef7fd332894c99" media="" id="highlight_theme_light"> <link rel="shortcut icon" href="data:image/svg+xml,<svg%20xmlns=%22http://www.w3.org/2000/svg%22%20viewBox=%220%200%20100%20100%22><text%20y=%22.9em%22%20font-size=%2290%22>%F0%9F%A7%A0</text></svg>"> <link rel="stylesheet" href="/assets/css/main.css?d41d8cd98f00b204e9800998ecf8427e"> <link rel="canonical" href="https://mattnolanlab.github.io/"> </head> <body class=" sticky-bottom-footer"> <header> <div class="container"> <img src="/assets/img/banner.png" class="banner" alt="Banner Image" style="width: 100%; height: auto;"> </div> <nav id="navbar" class="navbar container navbar-light navbar-expand-sm sticky-top" role="navigation"> <button class="navbar-toggler collapsed ml-auto" type="button" data-toggle="collapse" data-target="#navbarNav" aria-controls="navbarNav" aria-expanded="false" aria-label="Toggle navigation"> <span class="sr-only">Toggle navigation</span> <span class="icon-bar top-bar"></span> <span class="icon-bar middle-bar"></span> <span class="icon-bar bottom-bar"></span> </button> <div class="collapse navbar-collapse text-right" id="navbarNav"> <ul class="navbar-nav ml-auto flex-nowrap"> <li class="nav-item active"> <a class="nav-link" href="/">about <span class="sr-only">(current)</span> </a> </li> <li class="nav-item "> <a class="nav-link" href="/research/">research </a> </li> <li class="nav-item "> <a class="nav-link" href="/manual/">values </a> </li> <li class="nav-item "> <a class="nav-link" href="/values/">values </a> </li> <li class="nav-item "> <a class="nav-link" href="/publications/">publications </a> </li> <li class="nav-item "> <a class="nav-link" href="/repositories/">code & tools </a> </li> <li class="nav-item "> <a class="nav-link" href="/people-nolan/">Nolan group </a> </li> <li class="nav-item "> <a class="nav-link" href="/people-surmeli/">Sürmeli group </a> </li> </ul> </div> </nav> </header> <div class="container mt-5" role="main"> <div class="post"> <article> <div class="clearfix"> <p>We aim to understand the cellular and molecular basis for computations that underlie episodic memory. We are based in the <a href="https://discovery-brain-sciences.ed.ac.uk/" rel="external nofollow noopener" target="_blank">Centre for Discovery Brain Sciences</a> and the <a href="https://sidb.org.uk/" rel="external nofollow noopener" target="_blank">Simons Initative for the Developing Brain</a>. Our research follows four themes:</p> <p><strong>Circuit organisation.</strong> We are investigating the local and long-range organisation of circuits in the entorhinal cortex. We want to understand how molecular level organisation within the entorhinal cortex leads to architectural principles that are critical for memory storage and retrieval.</p> <p><strong>Circuit computations.</strong> We are using high density neural recordings and neural network models to investigate how entorhinal cortex circuits implement computations important for spatial memory.</p> <p><strong>Technology development.</strong> With collaborators in the <a href="https://www.eng.ed.ac.uk/research/institutes/imns/about" rel="external nofollow noopener" target="_blank">Institute for Integrated and Nano Systems</a> we are developing kilohertz frame rate cameras for imaging neural activity, and with collaborators in the <a href="https://web.inf.ed.ac.uk/anc" rel="external nofollow noopener" target="_blank">School of informatics</a> and the <a href="https://centreforstatistics.maths.ed.ac.uk/" rel="external nofollow noopener" target="_blank">Centre for Statistics</a> we are developing new tools for analysing the organisation and activation of neural circuits.</p> <p><strong>Circuit disorders.</strong> Many disorders of the brain appear to result from circuit level deficits. We believe that understanding the fundamental principles for neural circuit computation will be essential for understanding and treating disorders. We are addressing this by focusing on models of autism spectrum disorders and Alzheimer’s disease.</p> </div> <h2> <a href="/news/" style="color: inherit">news</a> </h2> <div class="news"> <div class="table-responsive"> <table class="table table-sm table-borderless"> <tr> <th scope="row" style="width: 20%">Mar 14, 2024</th> <td> We’re building the new website! </td> </tr> <tr> <th scope="row" style="width: 20%">Mar 14, 2024</th> <td> Harry’s <a href="https://elifesciences.org/articles/89356" rel="external nofollow noopener" target="_blank">paper</a> investigating grid firing and behaviour is out. A lot of hard work and a very exciting result. Well done Harry! </td> </tr> </table> </div> </div> </article> </div> </div> <footer class="sticky-bottom mt-5" role="contentinfo"> <div class="container"> © Copyright 2024 Nolan & Sürmeli. </div> </footer> <script src="https://cdn.jsdelivr.net/npm/[email protected]/dist/jquery.min.js" integrity="sha256-/xUj+3OJU5yExlq6GSYGSHk7tPXikynS7ogEvDej/m4=" crossorigin="anonymous"></script> <script src="/assets/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.jsdelivr.net/npm/[email protected]/js/mdb.min.js" integrity="sha256-NdbiivsvWt7VYCt6hYNT3h/th9vSTL4EDWeGs5SN3DA=" crossorigin="anonymous"></script> <script defer src="https://cdn.jsdelivr.net/npm/[email protected]/dist/masonry.pkgd.min.js" integrity="sha256-Nn1q/fx0H7SNLZMQ5Hw5JLaTRZp0yILA/FRexe19VdI=" crossorigin="anonymous"></script> <script defer src="https://cdn.jsdelivr.net/npm/[email protected]/imagesloaded.pkgd.min.js" integrity="sha256-htrLFfZJ6v5udOG+3kNLINIKh2gvoKqwEhHYfTTMICc=" crossorigin="anonymous"></script> <script defer src="/assets/js/masonry.js" type="text/javascript"></script> <script defer src="https://cdn.jsdelivr.net/npm/[email protected]/dist/medium-zoom.min.js" integrity="sha256-ZgMyDAIYDYGxbcpJcfUnYwNevG/xi9OHKaR/8GK+jWc=" crossorigin="anonymous"></script> <script defer src="/assets/js/zoom.js?85ddb88934d28b74e78031fd54cf8308"></script> <script src="/assets/js/no_defer.js?2930004b8d7fcd0a8e00fdcfc8fc9f24"></script> <script defer src="/assets/js/common.js?4a129fbf39254905f505c7246e641eaf"></script> <script defer src="/assets/js/copy_code.js?12775fdf7f95e901d7119054556e495f" type="text/javascript"></script> <script async src="https://d1bxh8uas1mnw7.cloudfront.net/assets/embed.js"></script> <script async src="https://badge.dimensions.ai/badge.js"></script> <script type="text/javascript">window.MathJax={tex:{tags:"ams"}};</script> <script defer type="text/javascript" id="MathJax-script" src="https://cdn.jsdelivr.net/npm/[email protected]/es5/tex-mml-chtml.js"></script> <script defer src="https://polyfill.io/v3/polyfill.min.js?features=es6"></script> </body> </html> |
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