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update documentation to link preprint
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MBoemo committed Nov 6, 2020
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4 changes: 3 additions & 1 deletion README.md
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Please see the [documentation](https://dnascent.readthedocs.io) for detailed usage instructions, descriptions of DNAscent's subprograms, and an example workflow.

## Citation
Muller CA, Boemo MA, Spingardi P, Kessler BM, Kriaucionis S, Simpson JT, Nieduszynski CA. Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads. *Nature Methods* 2019;16:429-436. [[Journal Link](https://www.nature.com/articles/s41592-019-0394-y)]
Please cite the following if you use DNAscent for your research:
- Boemo, MA. DNAscent v2: Detecting Replication Forks in Nanopore Sequencing Data with Deep Learning. *bioRxiv* 2020. [[Preprint Link](https://doi.org/10.1101/2020.11.04.368225)]
- Muller CA, Boemo MA, Spingardi P, Kessler BM, Kriaucionis S, Simpson JT, Nieduszynski CA. Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads. *Nature Methods* 2019;16:429-436. [[Journal Link](https://www.nature.com/articles/s41592-019-0394-y)]

## Questions and Bugs
Should any bugs arise or if you have basic usage questions, please raise a [GitHub issue](https://github.com/MBoemo/DNAscent/issues). For more detailed discussions or collaborations, please Email Michael Boemo at [email protected].
2 changes: 2 additions & 0 deletions docs/source/index.rst
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Please cite the following publication if you use DNAscent for your research:

Boemo, MA. DNAscent v2: Detecting Replication Forks in Nanopore Sequencing Data with Deep Learning. bioRxiv 2020. [`Preprint DOI <https://doi.org/10.1101/2020.11.04.368225>`_]

Muller CA, Boemo MA, Spingardi P, Kessler, BM, Kriaucionis S, Simpson JT, Nieduszynski CA. Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads. Nature Methods 2019;16:429-436. [`Journal DOI <https://doi.org/10.1038/s41592-019-0394-y>`_]

Bugs, Questions, and Comments
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6 changes: 3 additions & 3 deletions docs/source/releaseNotes.rst
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* Support for BrdU detection on GPUs,
* ``DNAscent forkSense`` to call replication origins and termination sites in both synchronously and asynchronously replicating cells at any point in S-phase,
* ``DNAscent align`` to align nanopore signals to reference,
* Significant increases to replication origin calling accuracy,
* Significant increases to replication origin calling accuracy and sensitivity,
* Visualisation utility for plotting output of multiple DNAscent executables as bedgraphs,
* Released with `Boemo, M.A. DNAscent v2: Detecting Replication Forks in Nanopore Sequencing Data with Deep Learning. bioRxiv 2020.
* Released with `Boemo, MA. DNAscent v2: Detecting Replication Forks in Nanopore Sequencing Data with Deep Learning. bioRxiv 2020. <https://doi.org/10.1101/2020.11.04.368225>`_.

v1.0.0
-----------------
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* Improvements to BrdU detection accuracy,
* ``DNAscent train`` to train Guassian mixture models from nanopolish eventalign.

v0.1
v0.1.0
-----------------

* HMM-based BrdU detection at ~160 thymidine-containing 6mers,
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