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Dr. Lucy Forrest's Lab authored Aug 18, 2020
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# AlignMe
Alignment of membrane proteins
Pairwise alignment of membrane protein sequences

## Required external libraries:
- boost library headers (boost.org), namely shared_ptr.hpp
## Required external libraries
Boost library headers (boost.org), namely shared_ptr.hpp

## Optional external code
[BLAST](https://blast.ncbi.nlm.nih.gov/Blast.cgi?PAGE_TYPE=BlastDocs&DOC_TYPE=Download) - for generating position specific substitution matrices
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[OCTOPUS](http://octopus.cbr.su.se/index.php?about=download) - for generating transmembrane predictions

## How to install:
## How to install
- change directory to the appropriate folder in your terminal
- type "make"
- the executable is created in this folder and ready to use

## How to use:
## How to use
- have a look at the manual AlignMe_manual.pdf and try out some examples
- scripts/use_best_parameters.pl can be used for running AlignMePST jobs if PSSM, secondary structure predictions, and transmembrane predictions are available.

## Online server:
- our online server is available at [http://www.bioinfo.mpg.de/AlignMe/](http://www.bioinfo.mpg.de/AlignMe/)
## Online server
Our online server is available at [http://www.bioinfo.mpg.de/AlignMe/](http://www.bioinfo.mpg.de/AlignMe/)

If you have questions about the usage of this program or discovered a
bug, then please post a message on github or write to: [email protected]
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