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Dr. Lucy Forrest's Lab
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Aug 18, 2020
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# AlignMe | ||
Alignment of membrane proteins | ||
Pairwise alignment of membrane protein sequences | ||
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## Required external libraries: | ||
- boost library headers (boost.org), namely shared_ptr.hpp | ||
## Required external libraries | ||
Boost library headers (boost.org), namely shared_ptr.hpp | ||
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## Optional external code | ||
[BLAST](https://blast.ncbi.nlm.nih.gov/Blast.cgi?PAGE_TYPE=BlastDocs&DOC_TYPE=Download) - for generating position specific substitution matrices | ||
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[OCTOPUS](http://octopus.cbr.su.se/index.php?about=download) - for generating transmembrane predictions | ||
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## How to install: | ||
## How to install | ||
- change directory to the appropriate folder in your terminal | ||
- type "make" | ||
- the executable is created in this folder and ready to use | ||
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## How to use: | ||
## How to use | ||
- have a look at the manual AlignMe_manual.pdf and try out some examples | ||
- scripts/use_best_parameters.pl can be used for running AlignMePST jobs if PSSM, secondary structure predictions, and transmembrane predictions are available. | ||
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## Online server: | ||
- our online server is available at [http://www.bioinfo.mpg.de/AlignMe/](http://www.bioinfo.mpg.de/AlignMe/) | ||
## Online server | ||
Our online server is available at [http://www.bioinfo.mpg.de/AlignMe/](http://www.bioinfo.mpg.de/AlignMe/) | ||
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If you have questions about the usage of this program or discovered a | ||
bug, then please post a message on github or write to: [email protected] | ||
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