Skip to content

Commit

Permalink
Added ref for rodent fMRI data quality issues.
Browse files Browse the repository at this point in the history
  • Loading branch information
Gab-D-G committed Oct 24, 2023
1 parent 0e3508f commit 67cf942
Show file tree
Hide file tree
Showing 2 changed files with 51 additions and 1 deletion.
50 changes: 50 additions & 0 deletions docs/_static/refs.bib
Original file line number Diff line number Diff line change
Expand Up @@ -649,6 +649,56 @@ @ARTICLE{Muschelli2014-vi
Specificity;RABIES documentation"
}

@ARTICLE{Grandjean2020-fa,
title = "Common functional networks in the mouse brain revealed by
multi-centre resting-state {fMRI} analysis",
author = "Grandjean, Joanes and Canella, Carola and Anckaerts, Cynthia and
Ayranc{\i}, G{\"u}lebru and Bougacha, Salma and Bienert, Thomas
and Buehlmann, David and Coletta, Ludovico and Gallino, Daniel
and Gass, Natalia and Garin, Cl{\'e}ment M and Nadkarni, Nachiket
Abhay and H{\"u}bner, Neele S and Karatas, Meltem and Komaki,
Yuji and Kreitz, Silke and Mandino, Francesca and Mechling, Anna
E and Sato, Chika and Sauer, Katja and Shah, Disha and Strobelt,
Sandra and Takata, Norio and Wank, Isabel and Wu, Tong and
Yahata, Noriaki and Yeow, Ling Yun and Yee, Yohan and Aoki, Ichio
and Chakravarty, M Mallar and Chang, Wei-Tang and Dhenain, Marc
and von Elverfeldt, Dominik and Harsan, Laura-Adela and Hess,
Andreas and Jiang, Tianzi and Keliris, Georgios A and Lerch,
Jason P and Meyer-Lindenberg, Andreas and Okano, Hideyuki and
Rudin, Markus and Sartorius, Alexander and Van der Linden,
Annemie and Verhoye, Marleen and Weber-Fahr, Wolfgang and
Wenderoth, Nicole and Zerbi, Valerio and Gozzi, Alessandro",
abstract = "Preclinical applications of resting-state functional magnetic
resonance imaging (rsfMRI) offer the possibility to
non-invasively probe whole-brain network dynamics and to
investigate the determinants of altered network signatures
observed in human studies. Mouse rsfMRI has been increasingly
adopted by numerous laboratories worldwide. Here we describe a
multi-centre comparison of 17 mouse rsfMRI datasets via a common
image processing and analysis pipeline. Despite prominent
cross-laboratory differences in equipment and imaging procedures,
we report the reproducible identification of several large-scale
resting-state networks (RSN), including a mouse default-mode
network, in the majority of datasets. A combination of factors
was associated with enhanced reproducibility in functional
connectivity parameter estimation, including animal handling
procedures and equipment performance. RSN spatial specificity was
enhanced in datasets acquired at higher field strength, with
cryoprobes, in ventilated animals, and under
medetomidine-isoflurane combination sedation. Our work describes
a set of representative RSNs in the mouse brain and highlights
key experimental parameters that can critically guide the design
and analysis of future rodent rsfMRI investigations.",
journal = "Neuroimage",
volume = 205,
pages = "116278",
month = jan,
year = 2020,
keywords = "Connectome; Default-mode network; Functional connectivity; ICA;
Seed-based;RABIES documentation",
language = "en"
}

@ARTICLE{Nickerson2017-gq,
title = "Using dual regression to investigate network shape and amplitude
in functional connectivity analyses",
Expand Down
2 changes: 1 addition & 1 deletion docs/analysis_QC.md
Original file line number Diff line number Diff line change
Expand Up @@ -12,7 +12,7 @@ nested_docs/group_stats.md
nested_docs/optim_CR.md
```

Data quality can have serious impacts on analysis outcomes, leading to false findings. Rodent imaging can suffer from spurious effects on connectivity measures if potential confounds are not well accounted for, or acquisition factors, such as anesthesia levels, can influence network activity (refs to Jo Multisite + RABIES preprint). To support interpretability, troubleshooting and reproducible research, RABIES includes a set of reports for conducting data quality assessment in individual scans and conducting quality control prior to network analysis at the group level. The reports are designed most specifically to evaluate the detectability of canonical brain networks and the impact of potential confounds (motion, physiological instabilities, and more).
Data quality can have serious impacts on analysis outcomes, leading to false findings. Rodent imaging can suffer from spurious effects on connectivity measures if potential confounds are not well accounted for, or acquisition factors, such as anesthesia levels, can influence network activity {cite}`Desrosiers-Gregoire2023-jm,Grandjean2020-fa`. To support interpretability, troubleshooting and reproducible research, RABIES includes a set of reports for conducting data quality assessment in individual scans and conducting quality control prior to network analysis at the group level. The reports are designed most specifically to evaluate the detectability of canonical brain networks and the impact of potential confounds (motion, physiological instabilities, and more).

This page describes how to generate the reports, our guidelines for conducting quality network of network analysis, and how to include those reports in a publication.

Expand Down

0 comments on commit 67cf942

Please sign in to comment.