Skip to content
This repository has been archived by the owner on Oct 23, 2023. It is now read-only.

Use msigdb for pathway analysis; perform additional analysis on specific db/pathway #474

Open
slsevilla opened this issue Aug 8, 2022 · 1 comment

Comments

@slsevilla
Copy link
Contributor

Utilizing Pipeliner output, perform pathway analysis in two ways:

  1. Pathway analysis msigdb - Performs GSEA and/or ORA analysis using msigdb with Pipeiner direct output. Should be able to intake db list with C1, and C2, and H sub-types. Output heatmaps, interactive DT, ridgeplot
  2. Pathway analysis extension - Performs Step Added STAR_QC to the all rules #1 if this hasn't been performed, and given a specific datasbase / pathway input will create pathway specific heatmaps for signficant genes, presents all genes that passed filtering present in pathway in a DT, and creates GSEA plot.
@slsevilla
Copy link
Contributor Author

scripts have been created and stored here: /data/CCBR_Pipeliner/sandbox/pathway_scripts

Sign up for free to subscribe to this conversation on GitHub. Already have an account? Sign in.
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant