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Protocols and templates for OHMC colaboratory

Project and reagent requests

Please visit this link to request a project/reagents. Reagents will be allocated on first come/first serve basis and alignment with one health theme.

Sample shipping

Do not send any samples to lab without first discussing project with Jordan. Please follow these guidelines when shipping samples. Note: all extracted samples must be sent in full-skirt 96 well plates. Samples to be extracted must be sent in screw top cryovials. A separate sheet with the sample layout is required to protect against damage to labels during shipping.

Protocol Selection

Nucleic Acid Extraction


Protocol 1: Extraction of gDNA using DNeasy PowerSoil QIAcube HT
Protocol 1A: Alternate protocol: Extraction of gDNA using DNeasy PowerSoil Individual Columns

Amplicon Sequencing


Protocol 1: Primary PCR
Protocol 2: Indexing PCR
Protocol 3: Pooling
Protocol 4: Size selection and cleanup

Metagenomic Sequencing


Under construction


Protocol 1: Scaled Illumina DNA Prep (flex)
Protocol 2: QC + Normalization with iSeq

Virome Sequencing


Protocol 1: VLP enrichment by CsCl gradient
Protocol 2: QIAamp MinElute Viral DNA extraction
Protocol 3: Scaled xGen ssDNA and low input DNA library prep

Library QC and Sequencing


Protocol 1: Library QC By Tapestation D1000
Protocol 2: Library Quantification by NebNext qPCR
Protocol 3: Loading P1 600 cycle kits on NextSeq 2000

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Protocols and templates for OHMC colaboratory

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