diff --git a/pathways/WP241/WP241.md b/pathways/WP241/WP241.md index ee891dc871..44d234a892 100644 --- a/pathways/WP241/WP241.md +++ b/pathways/WP241/WP241.md @@ -21,6 +21,7 @@ authors: - DeSl - Fehrhart - Eweitz +- Ddigles citedin: - link: PMC4127987 title: Polymorphisms in genes related to one-carbon metabolism are not related to @@ -50,15 +51,15 @@ description: 'This one-carbon metabolism pathway is centered around folate. Fola (vitamin B9) and of methionine. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP241 CPTAC Assay Portal]' -last-edited: 2022-01-29 +last-edited: 2023-07-18 ndex: 4f5ee643-8b61-11eb-9e72-0ac135e8bacf organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP241 - /instance/WP241 -- /instance/WP241_r120901 -revision: r120901 +- /instance/WP241_r126998 +revision: r126998 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP241.html diff --git a/pathways/WP4806/WP4806.md b/pathways/WP4806/WP4806.md index c3022f2bde..611a9e61ac 100644 --- a/pathways/WP4806/WP4806.md +++ b/pathways/WP4806/WP4806.md @@ -1,17 +1,17 @@ --- annotations: -- id: PW:0000298 +- id: PW:0001195 parent: signaling pathway type: Pathway Ontology - value: altered growth factor signaling pathway + value: tyrosine-specific protein kinase mediated signaling pathway - id: PW:0001537 parent: signaling pathway type: Pathway Ontology value: altered tyrosine-specific protein kinase mediated signaling pathway -- id: PW:0001195 +- id: PW:0000298 parent: signaling pathway type: Pathway Ontology - value: tyrosine-specific protein kinase mediated signaling pathway + value: altered growth factor signaling pathway authors: - Khanspers - Egonw @@ -33,15 +33,17 @@ description: Tyrosine kinase inhibitors (TKIs) are drugs that inhibit the phosph binds to the EGF-family of ligands. It activates several downstream signaling cascades, including MAPK, and leads to DNA synthesis and cell proliferation. Mutations and over-expression in EGFR is implicated in many cancers. The section of the pathway - outlined in pink corresponds to mechanisms of TKI resistance. -last-edited: 2021-05-14 + outlined in pink corresponds to mechanisms of TKI resistance. This pathway was + based on [https://www.kegg.jp/kegg-bin/show_pathway?hsa01521 KEGG]. +last-edited: 2023-07-18 ndex: 825693c1-8b6d-11eb-9e72-0ac135e8bacf organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP4806 - /instance/WP4806 -revision: null +- /instance/WP4806_r127006 +revision: r127006 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP4806.html @@ -57,14 +59,14 @@ schema-jsonld: kinase that binds to the EGF-family of ligands. It activates several downstream signaling cascades, including MAPK, and leads to DNA synthesis and cell proliferation. Mutations and over-expression in EGFR is implicated in many cancers. The section - of the pathway outlined in pink corresponds to mechanisms of TKI resistance. + of the pathway outlined in pink corresponds to mechanisms of TKI resistance. This + pathway was based on [https://www.kegg.jp/kegg-bin/show_pathway?hsa01521 KEGG]. keywords: - AKT1 - AKT2 - AKT3 - ARAF - AXL - - Apoptosis - BAD - BAX - BCL2 @@ -81,7 +83,6 @@ schema-jsonld: - EIF4EBP1 - ERBB2 - ERBB3 - - Epitheial-Mesenchymal Transition - Erlotinib - FGF2 - FGFR2 diff --git a/pathways/WP5345/WP5345.md b/pathways/WP5345/WP5345.md index d83ae2f1af..22f8aac00a 100644 --- a/pathways/WP5345/WP5345.md +++ b/pathways/WP5345/WP5345.md @@ -1,13 +1,13 @@ --- annotations: -- id: DOID:0060410 - parent: genetic disease - type: Disease Ontology - value: chromosome 1p36 deletion syndrome - id: PW:0000013 parent: disease pathway type: Pathway Ontology value: disease pathway +- id: DOID:0060410 + parent: genetic disease + type: Disease Ontology + value: chromosome 1p36 deletion syndrome authors: - KieranReidy - ElenaDR1 @@ -23,14 +23,14 @@ communities: - RareDiseases description: 1p36 deletion syndrome is a rare genetic disorder caused by the deletion of the most distal light band of the short arm of chromosome 1. -last-edited: 2023-07-10 +last-edited: 2023-07-18 organisms: - Homo sapiens redirect_from: - /index.php/Pathway:WP5345 - /instance/WP5345 -- /instance/WP5345_r126967 -revision: r126967 +- /instance/WP5345_r127005 +revision: r127005 schema-jsonld: - '@context': https://schema.org/ '@id': https://wikipathways.github.io/pathways/WP5345.html