diff --git a/packages/core/src/editor/dom-editor.ts b/packages/core/src/editor/dom-editor.ts
index f7a32f80e..5c0ff093d 100644
--- a/packages/core/src/editor/dom-editor.ts
+++ b/packages/core/src/editor/dom-editor.ts
@@ -29,6 +29,8 @@ import $, {
   DOMRange,
   DOMSelection,
   DOMStaticRange,
+  isDocument,
+  isShadowRoot,
   isDOMElement,
   normalizeDOMPoint,
   isDOMSelection,
@@ -122,7 +124,7 @@ export const DomEditor = {
     const el = DomEditor.toDOMNode(editor, editor)
     const root = el.getRootNode()
 
-    if ((root instanceof Document || root instanceof ShadowRoot) && root.getSelection != null) {
+    if ((isDocument(root) || isShadowRoot(root)) && Reflect.get(root, 'getSelection') != null) {
       return root
     }
     return el.ownerDocument
diff --git a/packages/core/src/editor/plugins/with-content.ts b/packages/core/src/editor/plugins/with-content.ts
index 1af7d7444..a5daf175f 100644
--- a/packages/core/src/editor/plugins/with-content.ts
+++ b/packages/core/src/editor/plugins/with-content.ts
@@ -370,7 +370,7 @@ export const withContent = <T extends Editor>(editor: T) => {
    * 重置 HTML 内容
    * @param html html string
    */
-  e.setHtml = (html: string = '') => {
+  e.setHtml = (html: string | null = '') => {
     // 记录编辑器当前状态
     const isEditorDisabled = e.isDisabled()
     const isEditorFocused = e.isFocused()
@@ -384,7 +384,7 @@ export const withContent = <T extends Editor>(editor: T) => {
     // https://github.com/wangeditor-team/wangEditor/issues/4754
     e.clear()
     // 设置新内容
-    const newContent = htmlToContent(e, html)
+    const newContent = htmlToContent(e, html == null ? '' : html)
     Transforms.insertFragment(e, newContent)
 
     // 恢复编辑器状态和选区
diff --git a/packages/core/src/text-area/event-handlers/beforeInput.ts b/packages/core/src/text-area/event-handlers/beforeInput.ts
index 86a4c2be4..e7adaeec0 100644
--- a/packages/core/src/text-area/event-handlers/beforeInput.ts
+++ b/packages/core/src/text-area/event-handlers/beforeInput.ts
@@ -8,7 +8,7 @@ import { DomEditor } from '../../editor/dom-editor'
 import { IDomEditor } from '../../editor/interface'
 import TextArea from '../TextArea'
 import { hasEditableTarget } from '../helpers'
-import { DOMStaticRange } from '../../utils/dom'
+import { DOMStaticRange, isDataTransfer } from '../../utils/dom'
 import { HAS_BEFORE_INPUT_SUPPORT } from '../../utils/ua'
 import { EDITOR_TO_CAN_PASTE } from '../../utils/weak-maps'
 
@@ -138,7 +138,7 @@ function handleBeforeInput(e: Event, textarea: TextArea, editor: IDomEditor) {
         if (!EDITOR_TO_CAN_PASTE.get(editor)) break // 不可默认粘贴
       }
 
-      if (data instanceof DataTransfer) {
+      if (isDataTransfer(data)) {
         // 这里处理非纯文本（如 html 图片文件等）的粘贴。对于纯文本的粘贴，使用 paste 事件
         editor.insertData(data)
       } else if (typeof data === 'string') {
diff --git a/packages/core/src/utils/dom.ts b/packages/core/src/utils/dom.ts
index 0402d65b3..8c6284d5d 100644
--- a/packages/core/src/utils/dom.ts
+++ b/packages/core/src/utils/dom.ts
@@ -68,6 +68,25 @@ if (empty) $.fn.empty = empty
 
 export default $
 
+import { toString } from './util'
+
+export const isDocument = (value: any): value is Document => {
+  return toString(value) === '[object HTMLDocument]'
+}
+
+export const isShadowRoot = (value: any): value is ShadowRoot => {
+  return toString(value) === '[object ShadowRoot]'
+}
+
+export const isDataTransfer = (value: any): value is DataTransfer => {
+  return toString(value) === '[object DataTransfer]'
+}
+
+const HTML_ELEMENT_STR_REG_EXP = /\[object HTML([A-Z][a-z]*)*Element\]/
+export const isHTMLElememt = (value: any): value is HTMLElement => {
+  return HTML_ELEMENT_STR_REG_EXP.test(toString(value))
+}
+
 // ------------------------------- 分割线，以下内容参考 slate-react dom.ts -------------------------------
 
 // COMPAT: This is required to prevent TypeScript aliases from doing some very
@@ -109,20 +128,14 @@ export const isDOMElement = (value: any): value is DOMElement => {
  * Check if a value is a DOM node.
  */
 export const isDOMNode = (value: any): value is DOMNode => {
-  const window = getDefaultView(value)
-  return (
-    !!window &&
-    // @ts-ignore
-    value instanceof window.Node
-  )
+  return value != null && typeof value.nodeType === 'number'
 }
 
 /**
  * Check if a value is a DOM selection.
  */
 export const isDOMSelection = (value: any): value is DOMSelection => {
-  const window = value && value.anchorNode && getDefaultView(value.anchorNode)
-  return !!window && value instanceof window.Selection
+  return toString(value) === '[object Selection]'
 }
 
 /**
@@ -343,7 +356,7 @@ export function walkTextNodes(
   handler: (textNode: DOMNode, parent: DOMElement) => void
 ) {
   // void elem 内部的 text 不处理
-  if (elem instanceof HTMLElement && elem.dataset.slateVoid === 'true') return
+  if (isHTMLElememt(elem) && elem.dataset.slateVoid === 'true') return
 
   for (let nodes = elem.childNodes, i = nodes.length; i--; ) {
     const node = nodes[i]
diff --git a/packages/core/src/utils/util.ts b/packages/core/src/utils/util.ts
index 7a6827c35..4c520f680 100644
--- a/packages/core/src/utils/util.ts
+++ b/packages/core/src/utils/util.ts
@@ -88,3 +88,5 @@ export function deReplaceHtmlSpecialSymbols(str: string) {
     .replace(/&trade;/g, '™')
     .replace(/&quot;/g, '"')
 }
+
+export const toString = (val: unknown): string => Object.prototype.toString.call(val)