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cdr_regions.md

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CDR loops (in []) identified manually and/or by abYsis.

Heavy Chains

TUPPD1 | H Chain 1

EVQLVKSGAEFKKPNDSLKITCKAS[GYTFTNTGT]NVHWVRQAPLKQLEWMGII[YTSTKD]INYAYEYQGRVEISKETSPSTAYLKLSSLKAENTAVYYCAT[EGQESVWHHNYLAMDQ]WGEGTRVTVSS

TUPPD1 | H Chain 2

QISLVESGPVLVKPNEQLKVACKTSGFTLS[SYGTVLN]WVRQAPGQRLEWLG[WVYIAGGGATFADATKT]RVAISVDKSLNDSYLAYNNVKAVDPGVYYCTR[TGTTTKTVSYYLYPRV]WGQGTTTTVSS

TUPPD1 | H Chain 3

QVELCQSGAEVKKPGSSLEASCKASGILLA[ENGTGMH]IVRKAPIEGLEWVN[GIYGSSTGVSYDPKFQS]RMSILIDKSEDTAYMHNSSIYTGDTVTYYCVN[EGVPTSHAHYYLSFKI]WGQYKTTTIQS

Light Chains

TUPPD1 | L Chain 1

ELVPTQAIRSLSLFLSEGLKISC[SSSRDIDNSSNIN]TELGSFHTRPERTKQDLIN[NKNNRAS]GVTELFSGRPSGKNFTLRISPIEADDAAITDILQRK[VEPPSNK]IVSVGTQYVIQ

TUPPD1 | L Chain 2

DIIMTNTPTNLYVSPGESICIIC[RSSKSGFDGNLVHT]YLKWYLQHPDIDPRWTIS[LLGN]REDQYPERFSNNLIYTDFIIDIQENVKKRHYNYIFSQI[RDSYPWPTI]GAGYWGDIK

TUPPD1 | L Chain 3

EIVMTQSPASLPVSPGERATVTC[RASESVSDSANGRGWLA]WLWQKPLQSPQLLIH[GASRSFS]GVGARFSDTGSVTDTAFKISRVETEDVGIYYC[NRRSRLGPLPLT]FAAGTGLEIQ