diff --git a/UefiCpuPkg/PiSmmCpuDxeSmm/SmmProfile.c b/UefiCpuPkg/PiSmmCpuDxeSmm/SmmProfile.c
index 4862cf075fed0..778b904f637da 100644
--- a/UefiCpuPkg/PiSmmCpuDxeSmm/SmmProfile.c
+++ b/UefiCpuPkg/PiSmmCpuDxeSmm/SmmProfile.c
@@ -714,24 +714,30 @@ InitSmmProfileCallBack (
   EFI_STATUS                 Status;
   EFI_SMM_VARIABLE_PROTOCOL  *SmmProfileVariable;
 
-  //
-  // Locate SmmVariableProtocol.
-  //
-  Status = gMmst->MmLocateProtocol (&gEfiSmmVariableProtocolGuid, NULL, (VOID **)&SmmProfileVariable);
-  ASSERT_EFI_ERROR (Status);
+  Status = EFI_SUCCESS;
+  if (!mIsStandaloneMm) {
+    //
+    // Locate SmmVariableProtocol.
+    //
+    Status = gMmst->MmLocateProtocol (&gEfiSmmVariableProtocolGuid, NULL, (VOID **)&SmmProfileVariable);
+    ASSERT_EFI_ERROR (Status);
 
-  //
-  // Save to variable so that SMM profile data can be found.
-  //
-  SmmProfileVariable->SmmSetVariable (
-                        SMM_PROFILE_NAME,
-                        &gEfiCallerIdGuid,
-                        EFI_VARIABLE_BOOTSERVICE_ACCESS | EFI_VARIABLE_RUNTIME_ACCESS,
-                        sizeof (mSmmProfileBase),
-                        &mSmmProfileBase
-                        );
+    //
+    // Save to variable so that SMM profile data can be found.
+    //
+    Status = SmmProfileVariable->SmmSetVariable (
+                                   SMM_PROFILE_NAME,
+                                   &gEfiCallerIdGuid,
+                                   EFI_VARIABLE_BOOTSERVICE_ACCESS | EFI_VARIABLE_RUNTIME_ACCESS,
+                                   sizeof (mSmmProfileBase),
+                                   &mSmmProfileBase
+                                   );
+    if (EFI_ERROR (Status)) {
+      DEBUG ((DEBUG_ERROR, "Set SmmProfile variable failure! Status = %r\n", Status));
+    }
+  }
 
-  return EFI_SUCCESS;
+  return Status;
 }
 
 /**