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Cross species data format #6

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Hrovatin opened this issue Jun 1, 2023 · 0 comments
Open

Cross species data format #6

Hrovatin opened this issue Jun 1, 2023 · 0 comments

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@Hrovatin
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Hrovatin commented Jun 1, 2023

Files prepared separately for cVAEs/scVI and scGLUE/Saturn

  • One to one orthologues:
    • For cVAE/scVI both species are in the same data: combined_orthologuesHVG.h5ad which has gene names mapped to mouse gene names
    • For scGLUE/Saturn they are in separate files: combined-hsPart_orthologuesHVG.h5ad (for hs/human) and combined-mmPart_orthologuesHVG.h5ad (for mm/mouse). Gene name correspondence (var names are species specific; gene symbols) is in combined_orthologuesHVG_geneMapping.tsv
  • Genes regardless of orthology:
    • Only applicable to scGLUE/Saturn, same format as described for one to one orthologues.

If some genes are not present in the provided Saturn embeddings I guess we can filter them out for Saturn. But most of the gene symbols should be present hopefully.

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