diff --git a/README.md b/README.md
index de578f6c..6e2c5c7e 100644
--- a/README.md
+++ b/README.md
@@ -32,6 +32,9 @@ This gem requires a Sass engine, so make sure you have **one** of these two gems
 
 Also ensure that `sprockets-rails` is at least v2.3.2.
 
+For wider browser compatibility, use [Autoprefixer][autoprefixer].
+If you are using Rails, add the `autoprefixer-rails` gem to your app and ensure you have a JavaScript runtime (e.g. NodeJS).
+
 `bundle install` and restart your server to make the files available through the pipeline.
 
 Import Bootstrap styles in `app/assets/stylesheets/application.scss`:
@@ -113,14 +116,6 @@ Refer to your framework's documentation on the subject.
 
 ## Configuration
 
-### Sass: Autoprefixer
-
-Bootstrap requires the use of [Autoprefixer][autoprefixer].
-[Autoprefixer][autoprefixer] adds vendor prefixes to CSS rules using values from [Can I Use](http://caniuse.com/).
-
-If you are using bootstrap with Rails, autoprefixer is set up for you automatically.
-Otherwise, please consult the [Autoprefixer documentation][autoprefixer].
-
 ### Sass: Individual components
 
 By default all of Bootstrap is imported.
diff --git a/Rakefile b/Rakefile
index fd1ae091..52402cce 100644
--- a/Rakefile
+++ b/Rakefile
@@ -57,7 +57,6 @@ task :debug do
   end
   require './lib/bootstrap'
   require 'term/ansicolor'
-  require 'autoprefixer-rails'
   path = Bootstrap.stylesheets_path
   %w(_bootstrap _bootstrap-reboot _bootstrap-grid).each do |file|
     filename = "#{path}/#{file}.scss"
@@ -66,7 +65,6 @@ task :debug do
           else
             Sass.compile(filename).css
           end
-    css = AutoprefixerRails.process(css)
     out = File.join('tmp', "#{file[1..-1]}.css")
     File.write(out, css)
     $stderr.puts Term::ANSIColor.green "Compiled #{out}"
diff --git a/bootstrap.gemspec b/bootstrap.gemspec
index 55b4f8f3..a0bd50c4 100644
--- a/bootstrap.gemspec
+++ b/bootstrap.gemspec
@@ -15,7 +15,6 @@ Gem::Specification.new do |s|
   s.required_ruby_version = '>= 2.3.3'
 
   s.add_runtime_dependency 'popper_js', '>= 2.11.8', '< 3'
-  s.add_runtime_dependency 'autoprefixer-rails', '>= 9.1.0'
 
   s.add_development_dependency 'rake'
 
diff --git a/lib/bootstrap/engine.rb b/lib/bootstrap/engine.rb
index 4d81db84..a907894e 100644
--- a/lib/bootstrap/engine.rb
+++ b/lib/bootstrap/engine.rb
@@ -1,6 +1,5 @@
 # frozen_string_literal: true
 
-require 'autoprefixer-rails'
 begin
   require 'dartsass-sprockets'
 rescue LoadError
diff --git a/test/dummy_rails/config/application.rb b/test/dummy_rails/config/application.rb
index 1a6ae466..8ed1d8e2 100644
--- a/test/dummy_rails/config/application.rb
+++ b/test/dummy_rails/config/application.rb
@@ -10,7 +10,6 @@
   require "#{framework}/railtie"
 end
 
-require 'autoprefixer-rails'
 require 'uglifier'
 require 'bootstrap'
 
@@ -29,4 +28,3 @@ class Application < Rails::Application
     end
   end
 end
-
diff --git a/test/gemfiles/rails_5_0.gemfile b/test/gemfiles/rails_5_0.gemfile
index 11cd1134..a18643d4 100644
--- a/test/gemfiles/rails_5_0.gemfile
+++ b/test/gemfiles/rails_5_0.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 5.0.0'
 gem 'activesupport', '~> 5.0.0'
-gem 'autoprefixer-rails', '>= 6.3.6.1'
 gem 'sassc-rails', '~> 2.0'
 
 gemspec path: '../../'
diff --git a/test/gemfiles/rails_5_1.gemfile b/test/gemfiles/rails_5_1.gemfile
index 884edc86..13f942c8 100644
--- a/test/gemfiles/rails_5_1.gemfile
+++ b/test/gemfiles/rails_5_1.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 5.1.0'
 gem 'activesupport', '~> 5.1.0'
-gem 'autoprefixer-rails', '>= 7.1.1'
 gem 'sassc-rails', '~> 2.0'
 
 gemspec path: '../../'
diff --git a/test/gemfiles/rails_5_2.gemfile b/test/gemfiles/rails_5_2.gemfile
index 18e980f1..767833c5 100644
--- a/test/gemfiles/rails_5_2.gemfile
+++ b/test/gemfiles/rails_5_2.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 5.2.8'
 gem 'activesupport', '~> 5.2.8'
-gem 'autoprefixer-rails', '>= 7.1.1'
 gem 'sassc-rails', '~> 2.0'
 
 gemspec path: '../../'
diff --git a/test/gemfiles/rails_6_0.gemfile b/test/gemfiles/rails_6_0.gemfile
index a92758dd..daeffa5f 100644
--- a/test/gemfiles/rails_6_0.gemfile
+++ b/test/gemfiles/rails_6_0.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 6.0.3'
 gem 'activesupport', '~> 6.0.3'
-gem 'autoprefixer-rails', '>= 9.7.6'
 gem 'sassc-rails', '~> 2.0'
 
 gemspec path: '../../'
diff --git a/test/gemfiles/rails_6_1.gemfile b/test/gemfiles/rails_6_1.gemfile
index a9b7f232..04342fbb 100644
--- a/test/gemfiles/rails_6_1.gemfile
+++ b/test/gemfiles/rails_6_1.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 6.1.3'
 gem 'activesupport', '~> 6.1.3'
-gem 'autoprefixer-rails', '>= 9.7.6'
 gem 'sassc-rails', '~> 2.0'
 
 gemspec path: '../../'
diff --git a/test/gemfiles/rails_7_0_dartsass.gemfile b/test/gemfiles/rails_7_0_dartsass.gemfile
index 8e38137e..6df9142d 100644
--- a/test/gemfiles/rails_7_0_dartsass.gemfile
+++ b/test/gemfiles/rails_7_0_dartsass.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 7.0.4'
 gem 'activesupport', '~> 7.0.4'
-gem 'autoprefixer-rails', '>= 9.7.6'
 gem 'dartsass-sprockets', '~> 3.0'
 
 gemspec path: '../../'
diff --git a/test/gemfiles/rails_7_0_sassc.gemfile b/test/gemfiles/rails_7_0_sassc.gemfile
index 28a4d05f..58fc0395 100644
--- a/test/gemfiles/rails_7_0_sassc.gemfile
+++ b/test/gemfiles/rails_7_0_sassc.gemfile
@@ -2,7 +2,6 @@ source 'https://rubygems.org'
 
 gem 'actionpack', '~> 7.0.4'
 gem 'activesupport', '~> 7.0.4'
-gem 'autoprefixer-rails', '>= 9.7.6'
 gem 'sassc-rails', '~> 2.0'
 
 gemspec path: '../../'
diff --git a/test/rails_test.rb b/test/rails_test.rb
index 046641e0..fc67b83d 100644
--- a/test/rails_test.rb
+++ b/test/rails_test.rb
@@ -12,11 +12,6 @@ def test_visit_root
     screenshot!
   end
 
-  def test_autoprefixer
-    get ActionController::Base.helpers.stylesheet_path('application.css')
-    assert_match(/-webkit-(?:transition|transform)/, response.body)
-  end
-
   def test_precompile
     Dummy::Application.load_tasks
     Rake::Task['assets:precompile'].invoke