cleo-v1-plasticity-expt

Code for the V1 plasticity disruption experiment (prospective experiment 2) in the Cleo publication. Original model from Wilmes and Clopath 2019. Adapted here by Nathan Cruzado to add closed-loop optogenetic control with Cleo.

Research was conducted in the SIPLab, led by Chris Rozell and Sankar Alagapan at Georgia Tech.

Setup

Install the conda environment:

mamba env create -f environment.yml
mamba activate wcm

(wcm refers to Wilmes-Clopath Model)

To replicate results in the paper, do all the following (all from repository root as the working directory):

Run the simulation for all target firing rates and no stimulation:
```
python run_cleo_sweep.py
```
Generate composite figures
```
python plot_parameter_sweep.py
```

This code has not been thoroughly tested, so please report any issues you encounter.