diff --git a/src/neuroglancer/ui/annotations.ts b/src/neuroglancer/ui/annotations.ts
index 8249a0b8b..eb821374e 100644
--- a/src/neuroglancer/ui/annotations.ts
+++ b/src/neuroglancer/ui/annotations.ts
@@ -349,9 +349,30 @@ export class AnnotationLayerView extends Tab {
     this.virtualList.element.addEventListener('mouseleave', () => {
       this.displayState.hoverState.value = undefined;
     });
-
+    const changeSelectedIndex = (offset: number) => {
+      const selectedIndex = this.getSelectedAnnotationIndex();
+      if (selectedIndex === undefined) return;
+      const nextAnnotation = this.listElements[selectedIndex+offset];
+      if (nextAnnotation) {
+        const {state, annotation} = nextAnnotation;
+        this.layer.selectAnnotation(state, annotation.id, true);
+        this.moveToAnnotation(annotation, state);
+      }
+    };
+    this.virtualList.element.addEventListener('action:select-previous-annotation', event => {
+      event.stopPropagation();
+      event.preventDefault();
+      changeSelectedIndex(-1);
+    });
+    this.virtualList.element.addEventListener('action:select-next-annotation', event => {
+      event.stopPropagation();
+      event.preventDefault();
+      changeSelectedIndex(1);
+    });
     const bindings = getDefaultAnnotationListBindings();
     this.registerDisposer(new MouseEventBinder(this.virtualList.element, bindings));
+    this.registerDisposer(new KeyboardEventBinder(this.virtualList.element, bindings));
+    this.virtualList.element.tabIndex = -1;
     this.virtualList.element.title = bindings.describe();
     this.registerDisposer(this.displayState.hoverState.changed.add(() => this.updateHoverView()));
     this.registerDisposer(
@@ -369,6 +390,17 @@ export class AnnotationLayerView extends Tab {
     this.updateSelectionView();
   }
 
+  private getSelectedAnnotationIndex() {
+    const {previousSelectedState: state} = this;
+    if (state === undefined) return;
+    const {annotationLayerState, annotationId} = state;
+    const attached = this.attachedAnnotationStates.get(annotationLayerState);
+    if (attached === undefined) return;
+    const index = attached.idToIndex.get(annotationId);
+    if (index === undefined) return;
+    return attached.listOffset + index;
+  }
+
   private getRenderedAnnotationListElement(
       state: AnnotationLayerState, id: AnnotationId, scrollIntoView: boolean = false): HTMLElement
       |undefined {
@@ -661,6 +693,18 @@ export class AnnotationLayerView extends Tab {
     this.updateSelectionView();
   }
 
+  private moveToAnnotation(annotation: Annotation, state: AnnotationLayerState) {
+    const chunkTransform = state.chunkTransform.value as ChunkTransformParameters;
+    const {layerRank} = chunkTransform;
+    const chunkPosition = new Float32Array(layerRank);
+    const layerPosition = new Float32Array(layerRank);
+    getCenterPosition(chunkPosition, annotation);
+    matrix.transformPoint(
+        layerPosition, chunkTransform.chunkToLayerTransform, layerRank + 1, chunkPosition,
+        layerRank);
+    setLayerPosition(this.layer, chunkTransform, layerPosition);
+  }
+
   private makeAnnotationListElement(annotation: Annotation, state: AnnotationLayerState) {
     const chunkTransform = state.chunkTransform.value as ChunkTransformParameters;
     const element = document.createElement('div');
@@ -757,14 +801,7 @@ export class AnnotationLayerView extends Tab {
     element.addEventListener('action:move-to-annotation', event => {
       event.stopPropagation();
       event.preventDefault();
-      const {layerRank} = chunkTransform;
-      const chunkPosition = new Float32Array(layerRank);
-      const layerPosition = new Float32Array(layerRank);
-      getCenterPosition(chunkPosition, annotation);
-      matrix.transformPoint(
-          layerPosition, chunkTransform.chunkToLayerTransform, layerRank + 1, chunkPosition,
-          layerRank);
-      setLayerPosition(this.layer, chunkTransform, layerPosition);
+      this.moveToAnnotation(annotation, state);
     });
 
     const selectionState = this.selectedAnnotationState.value;
diff --git a/src/neuroglancer/ui/default_input_event_bindings.ts b/src/neuroglancer/ui/default_input_event_bindings.ts
index 022972ada..150873819 100644
--- a/src/neuroglancer/ui/default_input_event_bindings.ts
+++ b/src/neuroglancer/ui/default_input_event_bindings.ts
@@ -68,6 +68,8 @@ export function getDefaultAnnotationListBindings() {
         {
           'click0': 'pin-annotation',
           'mousedown2': 'move-to-annotation',
+          'arrowup': 'select-previous-annotation',
+          'arrowdown': 'select-next-annotation',
         },
         {parents: [[getDefaultSelectBindings(), 0]]});
   }