Generate sequence based on natural one

[avivlazar]

Hi,
First of all, thank you for sharing ProGen2 code.
I read the article as part of my thesis, and started playing with the model.

My questions:

1. How may I generate a new sequence by ProGen2 which based on natural sequence?
   For example:
   Natural seq: "DQSVRKLVRKLPDEGLDREKVKTYLDKLGVDREELQKFSDAIGLESSGGS"
   A new generated seq: "GSSDIEITVEGKEQADKVIEEMKRRNLEVHVEEHNGQYIDKASLESSGGS"

2. In generation process, is it possible to define which station/s in natural sequence I want ProGen2 will change? if yes - how?
   Example: I want to change only the 3rd station in sequence, so:
   Natural seq: "DQSV..."
   Possible generated sequence: "DQGV..."
   So the 3rd station "S" was changed to "G".

Best Regards,
Aviv.

[Dongchengzhi]

Hello, they are also currently my questions.
Have you solved these problems?

[xubocheng]

I also have these questions.

[Solstice-Pan]

Hello, they are also currently my questions.
Have you solved these problems?