diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index d3588da1..e3d1d80a 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -134,18 +134,6 @@ jobs:
         include:
           - python-version: 2.7
             framework: FLASK_VERSION=0.9
-          - python-version: 3.3
-            framework: FLASK_VERSION=0.10.1
-          - python-version: 3.3
-            framework: FLASK_VERSION=0.11.1
-          - python-version: 3.3
-            framework: FLASK_VERSION=0.12.4
-          - python-version: 3.3
-            framework: FLASK_VERSION=1.0.2
-          - python-version: 3.3
-            framework: DJANGO_VERSION=1.6.11
-          - python-version: 3.3
-            framework: DJANGO_VERSION=1.8.19
           - python-version: 3.4
             framework: DJANGO_VERSION=1.7.11
           - python-version: 3.4
@@ -185,11 +173,6 @@ jobs:
       - name: Install dependencies
         run: pip install setuptools==39.2.0 --force-reinstall
 
-      - name: Python 3.3 dependencies
-        if: ${{ matrix.python-version == '3.3' }}
-        run: pip install --force-reinstall \
-          Werkzeug==0.14.1 six>=1.9.0 requests>=0.12.1 enum34 unittest2 blinker webob
-
       - name: Set the framework
         run: echo ${{ matrix.framework }} >> $GITHUB_ENV
 
diff --git a/setup.py b/setup.py
index db85c93d..165391d5 100644
--- a/setup.py
+++ b/setup.py
@@ -50,7 +50,6 @@
         "Programming Language :: Python :: 2",
         "Programming Language :: Python :: 2.7",
         "Programming Language :: Python :: 3",
-        "Programming Language :: Python :: 3.3",
         "Programming Language :: Python :: 3.4",
         "Programming Language :: Python :: 3.5",
         "Programming Language :: Python :: 3.6",
@@ -86,10 +85,6 @@
         'requests>=0.12.1; python_version >= "3.6"',
         'requests<2.26,>=0.12.1; python_version == "3.5"',
         'requests<2.22,>=0.12.1; python_version == "3.4"',
-        'requests<2.19,>=0.12.1; python_version == "3.3"',
-        'requests<1.2,>=0.12.1; python_version == "3.2"',
-        'requests<1.2,>=0.12.1; python_version == "3.1"',
-        'requests<1.2,>=0.12.1; python_version == "3.0"',
         'six>=1.9.0'
     ],
     tests_require=tests_require,