diff --git a/python/cudf/cudf/core/column/column.py b/python/cudf/cudf/core/column/column.py
index 2f7cc4ba176..b4f3f533d44 100644
--- a/python/cudf/cudf/core/column/column.py
+++ b/python/cudf/cudf/core/column/column.py
@@ -5,6 +5,7 @@
 import builtins
 import pickle
 import warnings
+from collections import abc
 from functools import cached_property
 from itertools import chain
 from types import SimpleNamespace
@@ -2384,12 +2385,16 @@ def as_column(
                     return cudf.core.column.ListColumn.from_sequences(
                         arbitrary
                     )
-                else:
+                elif isinstance(arbitrary, abc.Iterable) or isinstance(
+                    arbitrary, abc.Sequence
+                ):
                     data = as_column(
                         _construct_array(arbitrary, dtype),
                         dtype=dtype,
                         nan_as_null=nan_as_null,
                     )
+                else:
+                    raise e
     return data
 
 
diff --git a/python/cudf/cudf/tests/test_series.py b/python/cudf/cudf/tests/test_series.py
index 8be1f431ab3..83d22bbca2d 100644
--- a/python/cudf/cudf/tests/test_series.py
+++ b/python/cudf/cudf/tests/test_series.py
@@ -2204,3 +2204,12 @@ def test_series_contains(data, index):
     assert_eq(10 in ps, 10 in gs)
     assert_eq(True in ps, True in gs)
     assert_eq(False in ps, False in gs)
+
+
+def test_series_constructor_unbounded_sequence():
+    class A:
+        def __getitem__(self, key):
+            return 1
+
+    with pytest.raises(TypeError):
+        cudf.Series(A())