diff --git a/pyproject.toml b/pyproject.toml
index b1c9156d0..6e8a39ee4 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -1,2 +1,2 @@
 [build-system]
-requires = ["setuptools", "wheel", "numpy>=1.10", "pyparsing", "biopython"]
+requires = ["setuptools", "wheel", "numpy>=1.10", "pyparsing", "biopython", "scipy"]