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the KR normalization #307

Answered by robomics
Nuturetree asked this question in Q&A
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It does support it, in the sense that if a .hic or .[m]cool file contains KR weights, hictk can read and use those weights (e.g. when dumping interactions).

However, there are no plans to add KR support to hictk balance.
The reason being that I do not believe there is a way to implement KR efficiently, so a hictk implementation would be about as slow as e.g. juicer_tools.

If you have some tool that expects KR normalized weights, and that does not allow you to customize the weight names, what you could do is run one of the hictk balance subcommands and tell hictk to name the weights "KR".

Example:

hictk balance scale file.hic --name KR 

If you decide to use ICE, you most likely have to spe…

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Converted from issue

This discussion was converted from issue #305 on October 24, 2024 15:02.