the KR normalization #307
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Does hictk support KR standardization? |
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It does support it, in the sense that if a .hic or .[m]cool file contains KR weights, hictk can read and use those weights (e.g. when dumping interactions). However, there are no plans to add KR support to If you have some tool that expects KR normalized weights, and that does not allow you to customize the weight names, what you could do is run one of the Example: hictk balance scale file.hic --name KR If you decide to use ICE, you most likely have to specify |
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It does support it, in the sense that if a .hic or .[m]cool file contains KR weights, hictk can read and use those weights (e.g. when dumping interactions).
However, there are no plans to add KR support to
hictk balance
.The reason being that I do not believe there is a way to implement KR efficiently, so a hictk implementation would be about as slow as e.g.
juicer_tools
.If you have some tool that expects KR normalized weights, and that does not allow you to customize the weight names, what you could do is run one of the
hictk balance
subcommands and tell hictk to name the weights "KR".Example:
If you decide to use ICE, you most likely have to spe…