diff --git a/script/build b/script/build
index c6ce6e0a..d4d4e1f2 100755
--- a/script/build
+++ b/script/build
@@ -34,7 +34,7 @@ OT_CMAKE_NINJA_TARGET=${OT_CMAKE_NINJA_TARGET:-}
 NRF_PLATFORMS=(nrf52811 nrf52833 nrf52840)
 readonly NRF_PLATFORMS
 
-NRF_BUILD_TYPES=(UART_trans USB_trans SPI_trans_NCP soft_crypto soft_crypto_threading)
+NRF_BUILD_TYPES=(UART_trans USB_trans SPI_trans_NCP RTT_trans soft_crypto soft_crypto_threading)
 readonly NRF_BUILD_TYPES
 
 OT_SRCDIR="$(pwd)"
@@ -107,6 +107,10 @@ main()
                     OT_CMAKE_NINJA_TARGET=("ot-ncp-mtd" "ot-rcp")
                     options+=("${local_options[@]}" "-DOT_NCP_SPI=ON")
                     ;;
+                RTT_trans)
+                    OT_CMAKE_NINJA_TARGET=("ot-cli-mtd" "ot-rcp")
+                    options+=("${local_options[@]}" "-DOT_RTT_UART=ON")
+                    ;;
             esac
             ;;
         nrf52833)
@@ -122,6 +126,10 @@ main()
                     OT_CMAKE_NINJA_TARGET=("ot-ncp-ftd" "ot-ncp-mtd" "ot-rcp")
                     options+=("${local_options[@]}" "-DOT_NCP_SPI=ON")
                     ;;
+                RTT_trans)
+                    OT_CMAKE_NINJA_TARGET=("ot-cli-ftd" "ot-cli-mtd" "ot-rcp")
+                    options+=("${local_options[@]}" "-DOT_RTT_UART=ON")
+                    ;;
             esac
             ;;
         nrf52840)
@@ -137,6 +145,10 @@ main()
                     OT_CMAKE_NINJA_TARGET=("ot-ncp-ftd" "ot-ncp-mtd" "ot-rcp")
                     options+=("${local_options[@]}" "-DOT_NCP_SPI=ON" "-DOT_EXTERNAL_MBEDTLS=nordicsemi-mbedtls")
                     ;;
+                RTT_trans)
+                    OT_CMAKE_NINJA_TARGET=("ot-cli-ftd" "ot-cli-mtd" "ot-rcp")
+                    options+=("${local_options[@]}" "-DOT_RTT_UART=ON" "-DOT_EXTERNAL_MBEDTLS=nordicsemi-mbedtls")
+                    ;;
                 soft_crypto)
                     options+=("${local_options[@]}")
                     ;;
diff --git a/script/test b/script/test
index 935d0c06..aebe9d4a 100755
--- a/script/test
+++ b/script/test
@@ -68,6 +68,15 @@ main()
     rm -rf "$OT_BUILDDIR"
     "$(dirname "$0")"/build nrf52840 SPI_trans_NCP "${OT_OPTIONS[@]}"
 
+    rm -rf "$OT_BUILDDIR"
+    "$(dirname "$0")"/build nrf52811 RTT_trans "${OT_OPTIONS[@]}"
+
+    rm -rf "$OT_BUILDDIR"
+    "$(dirname "$0")"/build nrf52833 RTT_trans "${OT_OPTIONS[@]}"
+
+    rm -rf "$OT_BUILDDIR"
+    "$(dirname "$0")"/build nrf52840 RTT_trans "${OT_OPTIONS[@]}"
+
     rm -rf "$OT_BUILDDIR"
     "$(dirname "$0")"/build nrf52840 soft_crypto "${OT_OPTIONS[@]}"
 
diff --git a/src/CMakeLists.txt b/src/CMakeLists.txt
index f3857a0a..fffb99b7 100644
--- a/src/CMakeLists.txt
+++ b/src/CMakeLists.txt
@@ -26,7 +26,9 @@
 #  POSSIBILITY OF SUCH DAMAGE.
 #
 
-if(OT_NCP_SPI)
+if(OT_RTT_UART)
+    list(APPEND OT_PLATFORM_DEFINES "OPENTHREAD_UART_RTT_ENABLE=1")
+elseif(OT_NCP_SPI)
     list(APPEND OT_PLATFORM_DEFINES "SPIS_AS_SERIAL_TRANSPORT=1")
 else()
     option(OT_USB "enable nrf USB as serial transport support")
diff --git a/src/src/transport/transport.c b/src/src/transport/transport.c
index 074be886..c79df4d1 100644
--- a/src/src/transport/transport.c
+++ b/src/src/transport/transport.c
@@ -38,6 +38,8 @@
 
 #include "transport-drivers.h"
 
+#include "utils/uart_rtt.h"
+
 void nrf5TransportInit(bool aPseudoReset)
 {
     OT_UNUSED_VARIABLE(aPseudoReset);
@@ -82,6 +84,9 @@ void nrf5TransportProcess(void)
 #if (SPIS_AS_SERIAL_TRANSPORT == 1)
     nrf5SpiSlaveProcess();
 #endif
+#if (OPENTHREAD_UART_RTT_ENABLE == 1)
+    utilsUartRttProcess();
+#endif
 }
 
 bool nrf5TransportPseudoResetRequired(void)