-**OPR** is an open-source Python package designed to simplify and streamline primer design and analysis for biologists and bioinformaticians. **OPR** enables users to design, validate, and optimize primers with ease, catering to a wide range of applications such as PCR, qPCR, and sequencing. With a focus on user-friendliness and efficiency, **OPR** aims to bridge the gap between biological research and computational tools, making primer-related workflows faster and more reliable. +OPR is an open-source Python package designed to simplify and streamline primer design and analysis for biologists and bioinformaticians. OPR enables users to design, validate, and optimize primers with ease, catering to a wide range of applications such as PCR, qPCR, and sequencing. With a focus on user-friendliness and efficiency, OPR aims to bridge the gap between biological research and computational tools, making primer-related workflows faster and more reliable.