diff --git a/Cargo.lock b/Cargo.lock
index 44d8841e9..b0c6ba611 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -75,16 +75,15 @@ checksum = "4b46cbb362ab8752921c97e041f5e366ee6297bd428a31275b9fcf1e380f7299"
 
 [[package]]
 name = "anstream"
-version = "0.3.2"
+version = "0.5.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "0ca84f3628370c59db74ee214b3263d58f9aadd9b4fe7e711fd87dc452b7f163"
+checksum = "b1f58811cfac344940f1a400b6e6231ce35171f614f26439e80f8c1465c5cc0c"
 dependencies = [
  "anstyle",
  "anstyle-parse",
  "anstyle-query",
  "anstyle-wincon",
  "colorchoice",
- "is-terminal",
  "utf8parse",
 ]
 
@@ -114,9 +113,9 @@ dependencies = [
 
 [[package]]
 name = "anstyle-wincon"
-version = "1.0.1"
+version = "2.1.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "180abfa45703aebe0093f79badacc01b8fd4ea2e35118747e5811127f926e188"
+checksum = "58f54d10c6dfa51283a066ceab3ec1ab78d13fae00aa49243a45e4571fb79dfd"
 dependencies = [
  "anstyle",
  "windows-sys",
@@ -469,51 +468,42 @@ dependencies = [
 
 [[package]]
 name = "clap"
-version = "4.3.10"
+version = "4.4.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "384e169cc618c613d5e3ca6404dda77a8685a63e08660dcc64abaf7da7cb0c7a"
+checksum = "6a13b88d2c62ff462f88e4a121f17a82c1af05693a2f192b5c38d14de73c19f6"
 dependencies = [
  "clap_builder",
  "clap_derive",
- "once_cell",
-]
-
-[[package]]
-name = "clap-verbosity-flag"
-version = "2.0.1"
-source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "1eef05769009513df2eb1c3b4613e7fad873a14c600ff025b08f250f59fee7de"
-dependencies = [
- "clap",
- "log",
 ]
 
 [[package]]
 name = "clap_builder"
-version = "4.3.10"
+version = "4.4.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "ef137bbe35aab78bdb468ccfba75a5f4d8321ae011d34063770780545176af2d"
+checksum = "2bb9faaa7c2ef94b2743a21f5a29e6f0010dff4caa69ac8e9d6cf8b6fa74da08"
 dependencies = [
  "anstream",
  "anstyle",
  "clap_lex",
  "strsim",
+ "unicase",
+ "unicode-width",
 ]
 
 [[package]]
 name = "clap_complete"
-version = "4.3.1"
+version = "4.4.1"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "7f6b5c519bab3ea61843a7923d074b04245624bb84a64a8c150f5deb014e388b"
+checksum = "4110a1e6af615a9e6d0a36f805d5c99099f8bab9b8042f5bc1fa220a4a89e36f"
 dependencies = [
  "clap",
 ]
 
 [[package]]
 name = "clap_complete_fig"
-version = "4.3.1"
+version = "4.4.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "99fee1d30a51305a6c2ed3fc5709be3c8af626c9c958e04dd9ae94e27bcbce9f"
+checksum = "9e9bae21b3f6eb417ad3054c8b1094aa0542116eba4979b1b271baefbfa6b965"
 dependencies = [
  "clap",
  "clap_complete",
@@ -521,9 +511,9 @@ dependencies = [
 
 [[package]]
 name = "clap_derive"
-version = "4.3.2"
+version = "4.4.2"
 source = "registry+https://github.com/rust-lang/crates.io-index"
-checksum = "b8cd2b2a819ad6eec39e8f1d6b53001af1e5469f8c177579cdaeb313115b825f"
+checksum = "0862016ff20d69b84ef8247369fabf5c008a7417002411897d40ee1f4532b873"
 dependencies = [
  "heck",
  "proc-macro2",
@@ -1722,7 +1712,6 @@ dependencies = [
  "bzip2",
  "chrono",
  "clap",
- "clap-verbosity-flag",
  "clap_complete",
  "clap_complete_fig",
  "color-eyre",
@@ -3033,6 +3022,15 @@ version = "1.16.0"
 source = "registry+https://github.com/rust-lang/crates.io-index"
 checksum = "497961ef93d974e23eb6f433eb5fe1b7930b659f06d12dec6fc44a8f554c0bba"
 
+[[package]]
+name = "unicase"
+version = "2.7.0"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "f7d2d4dafb69621809a81864c9c1b864479e1235c0dd4e199924b9742439ed89"
+dependencies = [
+ "version_check",
+]
+
 [[package]]
 name = "unicode-bidi"
 version = "0.3.13"
diff --git a/packages_rs/nextclade-cli/Cargo.toml b/packages_rs/nextclade-cli/Cargo.toml
index 2b891e126..5d29296b0 100644
--- a/packages_rs/nextclade-cli/Cargo.toml
+++ b/packages_rs/nextclade-cli/Cargo.toml
@@ -11,9 +11,9 @@ publish = false
 
 [dependencies]
 assert2 = "=0.3.11"
-clap = { version = "=4.3.10", features = ["derive"] }
-clap_complete = "=4.3.1"
-clap_complete_fig = "=4.3.1"
+clap = { version = "=4.4.2", features = ["derive", "color", "unicode", "unstable-styles"] }
+clap_complete = "=4.4.1"
+clap_complete_fig = "=4.4.0"
 color-eyre = "=0.6.2"
 comfy-table = "=7.0.1"
 crossbeam = "=0.8.2"
diff --git a/packages_rs/nextclade-cli/src/cli/nextclade_cli.rs b/packages_rs/nextclade-cli/src/cli/nextclade_cli.rs
index bf45763db..d732b2e11 100644
--- a/packages_rs/nextclade-cli/src/cli/nextclade_cli.rs
+++ b/packages_rs/nextclade-cli/src/cli/nextclade_cli.rs
@@ -3,6 +3,7 @@ use crate::cli::nextclade_dataset_list::nextclade_dataset_list;
 use crate::cli::nextclade_loop::nextclade_run;
 use crate::cli::verbosity::{Verbosity, WarnLevel};
 use crate::io::http_client::ProxyConfig;
+use clap::builder::styling;
 use clap::{ArgGroup, CommandFactory, Parser, Subcommand, ValueEnum, ValueHint};
 use clap_complete::{generate, Generator, Shell};
 use clap_complete_fig::Fig;
@@ -27,10 +28,19 @@ lazy_static! {
   pub static ref SHELLS: Vec<&'static str> = ["bash", "elvish", "fish", "fig", "powershell", "zsh"].to_vec();
 }
 
+fn styles() -> styling::Styles {
+  styling::Styles::styled()
+    .header(styling::AnsiColor::Green.on_default() | styling::Effects::BOLD)
+    .usage(styling::AnsiColor::Green.on_default() | styling::Effects::BOLD)
+    .literal(styling::AnsiColor::Blue.on_default() | styling::Effects::BOLD)
+    .placeholder(styling::AnsiColor::Cyan.on_default())
+}
+
 #[derive(Parser, Debug)]
 #[clap(name = "nextclade")]
 #[clap(author, version)]
 #[clap(verbatim_doc_comment)]
+#[clap(styles = styles())]
 /// Viral genome alignment, mutation calling, clade assignment, quality checks and phylogenetic placement.
 ///
 /// Nextclade is a part of Nextstrain: https://nextstrain.org
diff --git a/packages_rs/nextclade/Cargo.toml b/packages_rs/nextclade/Cargo.toml
index 3e60a046d..b8b0962d1 100644
--- a/packages_rs/nextclade/Cargo.toml
+++ b/packages_rs/nextclade/Cargo.toml
@@ -18,10 +18,9 @@ auto_ops = "=0.3.0"
 bio = "=1.3.1"
 bio-types = "=1.0.0"
 chrono = { version = "=0.4.26", default-features = false, features = ["clock", "std", "wasmbind"] }
-clap = { version = "=4.3.10", features = ["derive"] }
-clap-verbosity-flag = "=2.0.1"
-clap_complete = "=4.3.1"
-clap_complete_fig = "=4.3.1"
+clap = { version = "=4.4.2", features = ["derive", "color", "unicode", "unstable-styles"] }
+clap_complete = "=4.4.1"
+clap_complete_fig = "=4.4.0"
 color-eyre = "=0.6.2"
 csv = "=1.2.2"
 ctor = "=0.2.2"